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A new passive immune strategy based on IgY antibodies as a key element to control neonatal calf diarrhea in dairy farms
Vega, Celina Guadalupe; Bok, Marina; Ebinger, Maren; Rocha, Lucía Alejandra; Rivolta, Alejandra Antonella; González Thomas, Valeria; Muntadas, Pilar; D’Aloia, Ricardo; Pinto, Verónica; Parreño, Viviana; Wigdorovitz, Andres (BMC, 2020-07)Background: Neonatal diarrhea remains one of the main causes of morbi-mortality in dairy calves under artificial rearing. It is often caused by infectious agents of viral, bacterial, or parasitic origin. Cows vaccination ... -
An indirect ELISA validated as diagnostic and vaccines quality control tool for bovine parainfluenza virus TYPE 3 (BPIV3)
Odeon, Maria Mercedes; Maidana, Silvina Soledad; Ferrecio, Carola Maria; Grazziotto, Noelia Magali; Pisano, Eddie; Alvarez, Irene; Rocha, Lucía Alejandra; Parreño, Gladys Viviana; Romera, Sonia Alejandra (CNRS (Francia), 2021-07)Serological assays, including enzyme-linked immunosorbent assays (ELISA), provide a useful tool to screen animals for the presence of antibodies (Abs) against a wide range of infectious agents (including viruses that cause ... -
Anti-VP6 VHH : an experimental treatment for rotavirus A-associated disease
Maffey, Lucia; Vega, Celina Guadalupe; Miño, Samuel; Garaicoechea, Lorena Laura; Parreño, Viviana (2016)Species A Rotaviruses (RVA) remain a leading cause of mortality in children under 5 years of age. Current treatment options are limited. We assessed the efficacy of two VP6-specific llama-derived heavy chain antibody ... -
Assessment of Influential Factors for Scours Associated with Cryptosporidium sp., Rotavirus and Coronavirus in Calves from Argentinean Dairy Farms
Bertoni, Emiliano Agustín; Barragán, Adrián A.; Bok, Marina; Vega, Celina Guadalupe; Martinez, Gabriela Marcela; Gil, José F.; Cimino, Rubén Oscar; Parreño, Gladys (MDPI, 2021-09)Scours is the most common disease in dairy calves, and it is a multifactorial syndrome complex. Cryptosporidium sp. (C. sp.), rotavirus group A (RVA), and bovine coronavirus (BCoV) are the three main pathogens associated ... -
Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries
Castells, Matias; Giannitti, Federico; Caffarena, Rubén Darío; Casaux, María Laura; Schild, Carlos; Castells, Daniel; Riet‑Correa, Franklin; Victoria, Matias; Parreño, Gladys; Colina, Rodney (Springer, 2019-11)Bovine coronavirus (BCoV) is a recognized cause of severe neonatal calf diarrhea, with a negative impact on animal welfare, leading to economic losses to the livestock industry. Cattle production is one of the most important ... -
Bovine rotavirus strains circulating in beef and dairy herds in Argentina from 2004 to 2010
Badaracco, Alejandra; Garaicoechea, Lorena Laura; Rodriguez, Daniela Vanesa; Louge Uriarte, Enrique Leopoldo; Odeon, Anselmo Carlos; Bilbao, Gladys; Galarza, Roxana Ivon; Abdala, Alejandro Ariel; Fernandez, Fernando Maria; Parreño, Gladys Viviana (Elsevier, 2012-08-17)Bovine Group A Rotavirus (RVA) is one of the main causes of neonatal calf diarrhea worldwide. The present study reports the genotyping of bovine RVA strains circulating in Argentinean cattle from 2004 to 2010. Additionally, ... -
Detection, risk factors and molecular diversity of norovirus GIII in cattle in Uruguay
Castells, Matias; Caffarena, Rubén Darío; Casaux, María Laura; Schild, Carlos; Castells, Felipe; Castells, Daniel; Victoria, Matías; Riet‑Correa, Franklin; Giannitti, Federico; Parreño, Viviana; Colina, Rodney (Elsevier, 2020-12)Uruguay is a leading exporter of bovine meat and dairy products, and cattle production is one of the principal economic backbones in this country. A main clinical problem faced by livestock farmers is neonatal calf diarrhea ... -
Development of diagnostic tools for IBDV detection using plants as bioreactors
Gomez, Evangelina Raquel; Cassani, María Florencia; Lucero, Maria Soledad; Parreño, Viviana; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (SpringerOpen, 2020-05)Infectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric ... -
Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
Aduriz Guerrero, Matías; Carossino, Mariano; Go, Y.Y.; Vincke, Cécile; Balasuriya, Udeni B.R.; Muyldermans, S.; Wigdorovitz, Andres; Barrandeguy, Maria Edith; Parreño, Viviana (2016)In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce ... -
Discovery and molecular characterization of a group A rotavirus strain detected in an Argentinean vicuña (Vicugna vicugna)
Badaracco, Alejandra; Matthijnssens, Jelle; Romero, Sandra Raquel; Heylen, Elisabeth; Zeller, Mark; Garaicoechea, Lorena Laura; Van Ranst, Marc; Parreño, Gladys Viviana (Elsevier, 2013-01-25)The wild vicuña (Vicugna vicugna) is one of the four species of native South American camelids (SACs) in addition to the wild guanaco, and their domesticated counterparts, alpaca and llama, respectively. Serological data ... -
Dynamics of neutralizing antibodies against Bovine respiratory syncytial virus in a dairy herd from Santa Fe Province, Argentina = Dinámica de anticuerpos neutralizantes contra el virus respiratorio sincitial bovino en un rodeo lechero de la provincia de Santa Fe, Argentina
Ferella, Alejandra; Perez Aguirreburiald, Maria Sol; Sammarruco, Romina Ayelén; Parreño, Viviana; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2020-05)Bovine respiratory syncytial virus (BRSV) is one of the most relevant agents responsible for respiratory disease in cattle from both dairy and beef farms. BRSV is spread by horizontal contact causing a constant presence ... -
Equine rotavirus in Argentinean foals : an overview
Parreño, Viviana; Miño, Samuel; Garaicoechea, Lorena Laura; Barrandeguy, Maria Edith (2016)The aim of the present work is to summarized our knowledge and discuss the future prospects regarding this important disease of foals. -
Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease
Nyblade, Charlotte; Parreño, Gladys Viviana; Zhou, Peng; Hensley, Casey; Oakes, Vanessa; Mahsoub, Hassan M.; Kiley, Kelsey; Frazier, Maggie; Frazier, Annie; Zhang, Yongrong; Feng, Hanping; Yuan, Lijuan (BioMed Central, 2022-06)Clostridioides difficile (C. difficile) is a gram-positive, spore-forming, anaerobic bacterium known to be the most common cause of hospital-acquired and antibiotic-associated diarrhea. C. difficile infection rates are on ... -
First report of group A rotavirus and bovine coronavirus associated with neonatal calf diarrhea in the northwest of Argentina
Bertoni, Emiliano Agustín; Aduriz Guerrero, Matías; Bok, Marina; Vega, Celina Guadalupe; Saif, Linda J.; Aguirre, Daniel Hector; Cimino, Rubén Oscar; Miño, Samuel; Parreño, Gladys Viviana (Springer, 2020-06)Group A rotavirus (RVA) and bovine coronavirus (BCoV) are the two main viral enteropathogens associated with neonatal calf diarrhea. The aim of the present survey was to investigate the epidemiology and the role of RVA and ... -
GII.4 human norovirus and G8P[1] bovine-like rotavirus in oysters (Crassostrea gigas) from Argentina
Mozgovoj, Marina Valeria; Miño, Samuel; Barbieri, Elena Susana; Tort López, Fernando; Montero, M. Victoria; Frydman, Camila Ayelén; Cap, Mariana; Barón, Pedro José; Colina, R.; Matthijnssens, Jelle; Parreño, Viviana Gladys (Elsevier, 2022-01-14)Bivalve mollusks have been widely recognized as an important source of foodborne virus. The aim of this work was to determine the presence of norovirus (NoV) and rotavirus (RVA) in Pacific cupped oyster (Crassostrea gigas) ... -
Influence of individual or group housing of newborn calves on rotavirus and coronavirus infection during the first 2 months of life
Bertoni, Emiliano Agustín; Bok, Marina; Vega, Celina Guadalupe; Martinez, Gabriela Marcela; Cimino, Rubén Oscar; Parreño, Gladys (Springer, 2021-01-03)Bovine rotavirus A (RVA) and bovine coronavirus (CoV) are the two main viral enteropathogens associated with neonatal calf diarrhea. The aim of the present work was to study the impact of group and individual housing systems ... -
Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994–2010
Bok, Marina; Miño, Samuel; Rodriguez, Daniela; Badaracco, Alejandra; Nuñes, I.; Souza, Sibele P.; Bilbao, G.; Louge Uriarte, Enrique Leopoldo; Galarza, Roxana Ivon; Vega, Celina Guadalupe; Odeon, Anselmo Carlos; Saif, LInda J.; Parreño, Gladys Viviana (Elsevier, 2015-12)Bovine coronavirus (BCoV) is an important viral pathogen associated with neonatal calf diarrhea. Our aim was to investigate the incidence of BCoV in diarrhea outbreaks in beef and dairy herds from Argentina during 1994–2010. ... -
Molecular characterization of equine rotavirus group A detected in Argentinean foals during 2009–2014
Miño, Samuel; Aduriz Guerrero, Matías; Barrandeguy, Maria Edith; Parreño, Viviana (2017-12)Equine rotavirus group A (RVA) has been detected in several countries worldwide since its first detection in 1975. Currently, equine RVA is considered the major cause of dehydrating diarrhea in foals younger than 3 months, ... -
Molecular detection of bovine Noroviruses in Argentinean dairy calves : circulation of a tentative new genotype
Ferragut, Fátima; Vega, Celina Guadalupe; Mauroy, Axel; Conceição-Neto, Nádia; Zeller, Mark; Heylen, Elisabeth; Louge Uriarte, Enrique Leopoldo; Bilbao, Gladys; Bok, Marina; Matthijnssens, Jelle; Thiry, Etienne; Badaracco, Alejandra; Parreño, Gladys Viviana (2016)Bovine noroviruses are enteric pathogens detected in fecal samples of both diarrheic and non-diarrheic calves from several countries worldwide. However, epidemiological information regarding bovine noroviruses is still ... -
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen II, D. Lee; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina Guadalupe; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreño, Gladys; Love, Kerry R.; Love, J. Christopher (BMC, 2021-05)Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ...