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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
Richetta, Matias Daniel; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Gravisaco, María José; Calamante, Gabriela; Berinstein, Analia (2017-01)Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ... -
Desarrollo y evaluación de un candidato vacunal para IBD producido en plantas: una alternativa a las vacunas tradicionales
Lucero, Maria Soledad (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2018)El Virus de la enfermedad infecciosa de la bursa (IBDV) es el agente etiológico responsable de una enfermedad aguda contagiosa e inmunosupresora que afecta pollos jóvenes y causa importantes pérdidas económicas. La vacunación ... -
Development of diagnostic tools for IBDV detection using plants as bioreactors
Gomez, Evangelina Raquel; Cassani, María Florencia; Lucero, Maria Soledad; Parreño, Viviana; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (SpringerOpen, 2020-05)Infectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric ... -
Developments in plant-based vaccines against diseases of concern in developing countries
Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Carrillo, Elisa Cristina; Berinstein, Analia (BENTHAM Open, 2010)Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where ... -
Differences in the virulence of two strains of Foot-and-Mouth Disease Virus Serotype A with the same spatiotemporal distribution
Garcia Nuñez, Maria Soledad; Konig, Guido Alberto; Berinstein, Analia; Carrillo, Elisa Cristina (Elsevier, 2010-01)During the 2000–2001 epidemic of Foot-and-Mouth Disease Virus (FMDV) in Argentina, two FMDV serotype A viruses were identified among others. Since different pathogenic properties between these virus strains were noticed ... -
Estudio de la relación del virus de la Bursitis Infecciosa con su hospedador. Análisis de la respuesta inmune y de la función y localización de la proteína viral VP5
Carballeda, Juan Manuel (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2015)Las aves representan un eslabón fundamental en la economía internacional. A nivel mundial, alrededor del 40% de la carne consumida es de origen aviar. La industria avícola ha experimentado en los últimos años un crecimiento ... -
Immunomodulatory effect of baculovirus in chickens : how it modifies the immune response against infectious bursal disease virus
Chimeno Zoth, Silvina Andrea; Carballeda, Juan Manuel; Gravisaco, María José; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Berinstein, Analia (2016)Several reports have shown that baculoviruses (BVs) have strong adjuvant properties on the mammalian immune system. Recent studies of our group demonstrated the ability of BV to stimulate the innate immunity in chickens. ... -
Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein
Carballeda, Juan Manuel; Maroniche, Guillermo Andrés; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (Elsevier, 2015-09)Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ... -
Plant-based vaccine candidate against Infectious bursal disease: an alternative to inactivated vaccines for breeder hens
Lucero, Maria Soledad; Richetta, Matias Daniel; Chimeno Zoth, Silvina Andrea; Jaton, Juan; Pinto, Silvina; Canet, Zulma Edith; Berinstein, Analia; Gomez, Evangelina Raquel (Elsevier, 2019-08)Infectious bursal disease (IBD) is an acute, highly contagious immunosuppressive disease that affects young birds causing important economic losses in the poultry industry worldwide. Strict hygiene management together with ... -
Propuesta de aplicación de la Teoría del Cambio al Proceso de Gestión “Evaluación de Procedimientos” que realiza el Comité Institucional para el Cuidado y Uso de Animales de Experimentación (CICUAE) INTA CNIA.
Berinstein, Analia; Montanari, Ana Luisa; Calamante, Gabriela (Ediciones INTA; Centro de Investigación en Ciencias Veterinarias y Agronómicas (CICVyA), 2021)Este trabajo se focaliza en la evaluación del proceso de gestión de procedimientos experimentales/educativos/de servicio que involucran el uso de animales que los agentes de INTA deben presentar ante el Comité Institucional ... -
Study of coinfection with local strains of infectious bursal disease virus and infectious bronchitis virus in specific pathogen-free chickens
Jaton, Juan Marcelo; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Gravisaco, María José; Pinto, Silvina; Vagnozzi, Ariel Eduardo; Craig, María Isabel; Di Giacomo, Sebastián; Berinstein, Analia; Chimeno Zoth, Silvina Andrea (Elsevier, 2023-12)Immunosuppressive diseases cause great losses in the poultry industry, increasing the susceptibility to infections by other pathogens and promoting a suboptimal response to vaccination. Among them, infectious bursal disease ... -
Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against Infectious Bursal Disease Virus
Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Carballeda, Juan Manuel; Gravisaco, María José; Berinstein, Analia (Elsevier, 2013-05-28)Infectious Bursal Disease Virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds. This disease causes important economic losses in the poultry industry worldwide. ...