Now showing items 1-14 of 14

    • A new cage-like particle adjuvant enhances protection of foot-and-mouth disease vaccine 

      Bidart, Juan Esteban; Kornuta, Claudia Alejandra; Gammella, Mariela; Gnazzo, Victoria; Soria, Ivana; Langellotti, Cecilia Ana; Mongini, Claudia; Galarza, Roxana Ivon; Calvinho, Luis Fernando; Lupi, Giuliana; Quattrocchi, Valeria; Marcipar, Ivan; Zamorano, Patricia Ines (Frontiers Media, 2020-07)
      Foot-and-Mouth Disease (FMD) is an acute viral disease that causes important economy losses. Vaccines with new low-cost adjuvants that stimulate protective immune responses are needed and can be assayed in a mouse model ...
    • A plasmid encoding the extracellular domain of CD40 ligand and MontanideTM GEL01 as adjuvants enhance the immunogenicity and the protection induced by a DNA vaccine against BoHV-1 

      Kornuta, Claudia Alejandra; Langellotti, Cecilia Ana; Bidart, , Juan Esteban; Soria, Ivana; Quattrocchi, Valeria; Gammella, Mariela; Cheuquepan Valenzuela, Felipe; Mignaqui, Ana Clara; Ferraris, Sergio; Charleston, Bryan; Hecker, Yanina; Moore, Prando Dadin; Zamorano, Patricia Ines (Elsevier, 2021-02)
      DNA vaccines are capable of inducing humoral and cellular immunity, and are important to control bovine herpesvirus 1 (BoHV-1), an agent of the bovine respiratory disease complex. In previous work, a DNA plasmid that encodes ...
    • An improved DNA vaccine against bovine herpesvirus-1 using CD40L and a chemical adjuvant induces specific cytotoxicity in mici 

      Langellotti, Cecilia Ana; Gammella, Mariela; Soria, Ivana; Bellusci, Carolina; Quattrocchi, Valeria; Vermeulen, Elba Monica; Mongini, Claudia; Zamorano, Patricia Ines (Mary Ann Liebert, 2021-03)
      Bovine herpesvirus-1 (BoHV-1) uses many mechanisms to elude the immune system; one of them is spreading intracellularly, even in the presence of specific antiviral antibodies. Cytotoxic T lymphocytes (CTLs) are necessary ...
    • Bovine interferon lambda Is a potent antiviral against SARS-CoV-2 infection in vitro 

      Cardoso, Nancy; Mansilla, Florencia Celeste; Benedetti, Estefanía; Turco, Cecilia Soledad; Barone, Lucas Jose; Iserte, Javier Alonso; Soria, Ivana; Baumeister, Elsa; Capozzo, Alejandra (Frontiers Media, 2020-11)
      Interferon lambda (IFN-λ) is an antiviral naturally produced in response to viral infections, with activity on cells of epithelial origin and located in the mucosal surfaces. This localized activity results in reduced ...
    • Cyclophosphamide enhances the release of tumor exosomes that elicit a specific immune response in vivo in a murine T-cell lymphoma 

      Cocozza, Federico; Menay, Florencia; Tsacalian, Rodrigo Farid; Elisei, Analia; Sampedro, Pura; Soria, Ivana; Waldner, Claudia Inés; Gravisaco, María José; Mongini, Claudia (Elsevier, 2019-03)
      Exosomes are 60–150 nm small extracellular vesicles (EVs) released by most cells. Tumor-cell-derived exosomes, used as a vaccine, elicit a specific cytotoxic response against tumor cells, usually with a greater immunogenicity ...
    • Dendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle 

      Soria, Ivana; Quattrocchi, Valeria; Langellotti, Cecilia Ana; Gammella, Mariela; Di Giacomo, Sebastián; Garcia de la Torre, Beatriz; Andreu, David; Montoya, Maria; Sobrino, Francisco; Blanco, Esther; Zamorano, Patricia Ines (2017-09)
      Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A synthetic vaccine candidate consisting of dendrimeric peptides harbouring two copies of a B-epitope [VP1(136–154)] linked ...
    • Dendritic cell targeting in cultured fish in Argentina for vaccine development 

      Ghersa, Federica; Soria, Ivana; Quattrocchi, Valeria; Gammella, Mariela; Langellotti, Cecilia Ana; Zamorano, Patricia Ines; Rauque, Carlos Alejandro; Pappalardo, Juan Sebastián (Edición del Autor, 2019)
      In Argentina two main species present an important economic value, these are Pacú (Piaractus mesopotamicus, Pm) and Rainbow Trout (Oncorhynchus mykiss, Om). Due to stress and changing environmental conditions cultured fish ...
    • FMD empty capsids combined with the immunostant particle adjuvant -ISPA or ISA206 induce protective immunity against foot and mouth disease virus 

      Bidart, Juan Esteban; Mignaqui, Ana Clara; Kornuta, Claudia Alejandra; Lupi, Giuliana; Gammella, Mariela; Soria, Ivana; Galarza, Roxana Ivon; Ferella, Alejandra; Cardillo, Sabrina Beatriz; Langellotti, Cecilia Ana; Quattrocchi, Valeria; Durocher, Yves; Wigdorovitz, Andres; Marcipar, Ivan; Zamorano, Patricia Ines (Elsevier, 2021-05)
      Foot and Mouth Disease Virus (FMDV) causes economy losses and is controlled by vaccination in many countries. Vaccine formulations based on empty capsids or Virus-Like Particles (VLPs) have the advantage of avoiding the ...
    • Foot-and-mouth disease virus infection of dendritic cells triggers phosphorylation of ERK1/2 inducing class I presentation and apoptosis 

      Langellotti, Cecilia Ana; Cesar, Gonzalo; Soria, Ivana; Quattrocchi, Valeria; Jancic, Carolina Cristina; Zamorano, Patricia Ines; Vermeulen, Elba Monica (Elsevier, 2015-09)
      Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. This pathology is caused by foot-and-mouth disease virus (FMDV). Over time, the development of vaccines to prevent the spread of ...
    • Immune Response and Partial Protection against Heterologous Foot-and-Mouth Disease Virus Induced by Dendrimer Peptides in Cattle 

      Soria, Ivana; Quattrocchi, Valeria; Langellotti, Cecilia Ana; Perez Filgueira, Daniel Mariano; Pega, Juan Franco; Gnazzo, Victoria; Romera, Sonia Alejandra; Schammas, Juan Manuel; Bucafusco, Danilo; Di Giacomo, Sebastián; García de la Torre, Beatriz; Andreu, David; Sobrino, Francisco; Blanco, Esther; Zamorano, Patricia Ines (2018-04)
      Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ...
    • Immune response to Neospora caninum live tachyzoites in prepubertal female calves 

      Hecker, Yanina; Regidor-Cerrillo, Javier; Fiorani, Franco; Horcajo, Pilar; Soria, Ivana; Gual, Ignacio; Torioni, Susana Marta; Campero, Lucia; Echaide, Ignacio Eduardo; Alvarez-García, Gema; Ortega-Mora, Luis; Zamorano, Patricia Ines; Venturini, María Clara; Odeon, Anselmo Carlos; Canton, German Jose; Moore, Prando Dadin (Springer Berlin, 2019-09-04)
      The aim of the present study was to characterize the specific immune response in prepubertal female calves inoculated with Neospora caninum. Forty-eight N. caninum-seronegative 6-month-old Angus female calves were randomly ...
    • MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1 

      Kornuta, Claudia Alejandra; Bidart, , Juan Esteban; Soria, Ivana; Gammella, Mariela; Quattrocchi, Valeria; Pappalardo, Juan Sebastián; Salmaso, Stefano; Torchilin, Vladimir P.; Cheuquepan Valenzuel, Felipe Andres; Hecker, Yanina; Moore, Dadin P.; Zamorano, Patricia Ines; Langellotti, Cecilia Ana (Wiley, 2020-07)
      New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ...
    • Mouse model as an efficacy test for foot‐and‐mouth disease vaccines 

      Gnazzo, Victoria; Quattrocchi, Valeria; Soria, Ivana; Pereyra, Erica Vanesa; Langellotti, Cecilia Ana; Pedemonte, Andrea; López, Virginia; Marangunich, Laura An; Zamorano, Patricia Ines (Wiley, 2020-04)
      Protection against foot‐and‐mouth disease virus (FMDV) has been linked to the development of a humoral response. In Argentina, the official control tests for assessing the potency of FMD vaccines are protection against ...
    • TLR activation, immune response and viral protection elicited in cattle by a commercial vaccine against Bovine Herpesvirus-1 

      Kornuta, Claudia Alejandra; Cheuquepan Valenzuel, Felipe Andres; Bidart, , Juan Esteban; Soria, Ivana; Gammella, Mariela; Quattrocchi, Valeria; Hecker, Yanina; Moore, Prando Dadin; Romera, Sonia Alejandra; Marin, Maia Solange; Zamorano, Patricia Ines; Langellotti, Cecilia Ana (Elsevier, 2022-01)
      The innate and acquired immune response induced by a commercial inactivated vaccine against Bovine Herpesvirus-1 (BoHV-1) and protection conferred against the virus were analyzed in cattle. Vaccination induced high levels ...