Now showing items 1-5 of 5

    • Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles 

      Bigi, María Mercedes; Vazquez, Cristina Lourdes; Castelão, Ana Beatriz C.; Garcia, Elizabeth Andrea; Cataldi, Angel Adrian; Jackson, Mary; McNeil, Michael; Soria, Marcelo Abel; Zumarraga, Martin Jose; Cabruja, Matias; Gago, Gabriela; Blanco, Federico Carlos; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Araujo, Flabio Ribeiro de; Bigi, Fabiana (Elsevier, 2019-12)
      Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ...
    • Bovine macrophages responses to the infection with virulent and attenuated Leptospira interrogans serovar Pomona 

      Nagel, Ariel Gaston; Vazquez, Cristina Lourdes; Etulain, Julia; Blanco, Federico Carlos; Gravisaco, María José; Gomez, Ricardo Martín; Caimi, Karina Cynthia (Elsevier, 2019-06)
      Leptospirosis is a zoonosis, caused by pathogenic spirochetes of the genus Leptospira. Although cattle are usually the maintenance hosts of serovar Hardjo, Pomona is the most frequent serovar circulating in Argentina. The ...
    • Characterization of the two component regulatory system PhoPR in Mycobacterium bovis 

      Garcia, Elizabeth Andrea; Blanco, Federico Carlos; Bigi, María Mercedes; Vazquez, Cristina Lourdes; Forrellad, Marina Andrea; Rocha, Rosana Valeria; Golby, Paul; Soria, Marcelo Abel; Bigi, Fabiana (Elsevier, 2018-08)
      Mycobacterium bovis is the causative agent of bovine tuberculosis and is a member of Mycobacterium tuberculosis complex, which causes tuberculosis in a number of mammals including humans. Previous studies have shown that ...
    • Mycobacterium bovis requires P27 (LprG) to arrest phagosome maturation and replicate within bovine macrophages 

      Vazquez, Cristina Lourdes; Bianco, María Veronica; Blanco, Federico Carlos; Forrellad, Marina Andrea; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (2017-03)
      Mycobacterium bovis causes tuberculosis in a wide variety of mammals, with strong tropism for cattle and eventually humans. P27, also called LprG, is among the proteins involved in the mechanisms of the virulence and ...
    • Rv2617c and P36 are virulence factors of pathogenic mycobacteria involved in resistance to oxidative stress 

      Forrellad, Marina Andrea; Vazquez, Cristina Lourdes; Blanco, Federico Carlos; Klepp, Laura Ines; Garcia, Elizabeth Andrea; Rocha, Rosana Valeria; Villafañe, Luciana Maria; Bigi, María Mercedes; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (Taylor & Francis, 2019-12)
      In this study, we characterized the role of Rv2617c in the virulence of Mycobacterium tuberculosis. Rv2617c is a protein of unknown function unique to M. tuberculosis complex (MTC) and Mycobacterium leprae. In vitro, this ...