Now showing items 1-7 of 7

    • Balance between retroviral latency and transcription : based on HIV model 

      Pluta, Aneta; Jaworski, Juan Pablo; Cortés-Rubio, César N. (MDPI, 2021-01)
      The representative of the Lentivirus genus is the human immunodeficiency virus type 1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS). To date, there is no cure for AIDS because of the existence ...
    • Bovine leukemia virus becomes established in dairy herds before the first lactation 

      Merlini, Ramiro; Gutierrez, Gerónimo; Alvarez, Irene; Jaworski, Juan Pablo; Carignano, Hugo Adrian; Poli, Mario Andres; Willems, Luc; Trono, Karina Gabriela (2016)
      In this work, we studied seven groups of pregnant heifers from a consortium of dairy farms heavily infected with bovine leukemia virus (BLV). ELISA testing showed that the seroprevalence ranges of BLV in heifers between ...
    • Neutralizing monoclonal antibodies to fight HIV-1 : on the threshold of success 

      Jaworski, Juan Pablo; Vendrell, Alejandrina; Chiavenna, Sebastián Matias (2017)
      Anti-human immunodeficiency virus type-1 (anti-HIV-1) neutralizing monoclonal antibodies are broadening the spectrum of pre- and post-exposure treatment against HIV-1. A better understanding of how these antibodies develop ...
    • Short communication: Relationship between the level of bovine leukemia virus antibody and provirus in blood and milk of cows from a naturally infected herd 

      Jaworski, Juan Pablo; Porta, Natalia Gabriela; Gutierrez, Gerónimo; Politzki, Romina Paula; Alvarez, Irene; Galarza, Roxana Ivon; Abdala, Alejandro Ariel; Calvinho, Luis Fernando; Trono, Karina Gabriela (2016)
      We explored the relationship between the level of bovine leukemia virus antibodies and provirus load during natural infection. For that purpose, a set of 50 blood and milk paired samples were analyzed for the presence of ...
    • Spontaneous virus reactivation in cattle chronically infected with bovine leukemia virus 

      Jaworski, Juan Pablo; Petersen, Marcos Iván; Carignano, Hugo; Trono, Karina Gabriela (BioMed Central, 2019)
      Background: The absence of virus expression during the chronic stage of bovine leukemia virus (BLV) infection and its reactivation upon ex vivo culture has become a long-lived Dogma. During the chronic stage of BLV ...
    • State of the art in anti-cancer mAbs 

      Chiavenna, Sebastián Matias; Jaworski, Juan Pablo; Vendrell, Alejandrina (2017-02-20)
      Following Milstein’s discovery, the monoclonal antibodies (mAbs) became a basic tool for biomedical science. In cancer field, since the first mAb was approved by the FDA a great improvement took place making of them a ...
    • Vaccination against δ-retroviruses : the bovine leukemia virus paradigm 

      Gutierrez, Gerónimo; Rodriguez, Sabrina M.; de Brogniez, Alix; Gillet, Nicolas A.; Golime, Ramarao; Burny, Arsene; Jaworski, Juan Pablo; Alvarez, Irene; Vagnoni, Lucas Emilio; Trono, Karina Gabriela; Willems, Luc (2014-06)
      Bovine leukemia virus (BLV) and human T-lymphotropic virus type 1 (HTLV-1) are closely related d-retroviruses that induce hematological diseases. HTLV-1 infects about 15 million people worldwide, mainly in subtropical ...