Now showing items 1-10 of 10

    • Brucella spp. Lumazine synthase as a novel immunomodulator to produce egg yolk antibodies 

      Bellido, Demian; Chacana, Pablo; Mozgovoj, Marina Valeria; Gonzalez, Diego; Goldbaum, Fernando Alberto; Wigdorovitz, Andres; Dus Santos, Maria Jose (Scientific Research, 2012-02)
      Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It has been previously described as a carrier of peptides or proteins to increase their immunogenicity in different animal species, but ...
    • Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro 

      Ferella, Alejandra; Bellido, Demian; Chacana, Pablo; Wigdorovitz, Andres; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2012)
      Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive ...
    • IgY technology: producing antibodies from a 3Rs perspective 

      Leiva, Carlos Leónidas; Casanova, Natalia Andrea; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (2018-07)
    • IgY-based antivenom against Bothrops alternatus: Production and neutralization efficacy 

      Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Farace, Mariano; Geoghegan, Patricia; Brero, Luisa; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo Anibal (Elsevier, 2019-05)
      Antivenom for the treatment of bothropic snakebite is a priority for public health institutions from Latin America. An alternative to the conventional antivenom production is based on the use of egg yolk antibodies – ...
    • IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials 

      Leiva, Carlos; Gallardo, Mauro Julián; Casanova, Natalia Andrea; Terzolo, Horacio; Chacana, Pablo (Elsevier, 2020-04)
      IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its ...
    • In vitro inhibitory activity of IgY antibodies against Salmonella ser. newport isolated from horses 

      Bustos, Carla Paola; Leiva, Carlos Leónidas; Gambarotta, Mariana; Guida, Nora; Chacana, Pablo (Elsevier, 2021-08)
      Equine salmonellosis is caused by several Salmonella serotypes, including Salmonella Newport, which cause enterocolitis and diarrhea. Treatment usually includes the administration of antibiotics. However, since multidrug-resistant ...
    • In vivo neutralization of bee venom lethality by IgY antibodies 

      Leiva, Carlos Leónidas; Geoghegan, Patricia; Lammer, Mónica; Cangelosi, Adriana; Mariconda, Virginia; Celi Castillo, Ana Beatriz; Brero, Luisa; Chacana, Pablo (Elsevier, 2021-07)
      Bee venom is a complex mixture of molecules, among which melittin and phospholipase A2 (PLA2) are the toxic components involved in envenoming accidents with multiple honeybee stings. Traditionally, the treatment of envenomings ...
    • Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry 

      Dominguez, Johanna Elizabeth; Viñas, María Rosa; Herrera, Mariana; Moroni, Mirian; Gutkind, Gabriel Omar; Mercado, Elsa Cristina; Di Conza, José Alejandro; Chacana, Pablo (Wiley, 2021-02)
      In the last 10 years, Salmonella Heidelberg has been extensively isolated from poultry in several countries. In this context, molecular characterization is essential to understand whether the strains have entered the farms ...
    • Reproducción experimental de la infección de Eimeria spp. en pollos parrilleros a partir de un aislamiento de campo 

      Tomazic, Mariela Luján; Delgado, Fernando Oscar; Balbiani, Facundo; Jauregui, Gloria R.; Chacana, Pablo; Schapiro, Javier Hernan; De Franceschi, M.; Palacios, L.; Rodriguez, Anabel Elisa (FundaVet, 2019-06)
      La coccidiosis es la afección parasitaria de mayor trascendencia económica en explotaciones avícolas. La producen protozoarios del género Eimeria que afectan el intestino delgado y los ciegos de las aves. Su control se ...
    • Simultaneous carriage of mcr-1 and other antimicrobial resistance determinants in Escherichia coli from poultry 

      Dominguez, Johanna Elizabeth; Redondo, Leandro Martín; Figueroa Espinosa, Roque A.; Cejas, Daniela; Gutkind, Gabriel Omar; Chacana, Pablo; Di Conza, José Alejandro; Fernandez Miyakawa, Mariano Enrique (Frontiers Media, 2018-07)
      The use of antimicrobial growth promoters (AGPs) in sub-therapeutic doses for long periods promotes the selection of resistant microorganisms and the subsequent risk of spreading this resistance to the human population and ...