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A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing
Cacciabue, Marco Polo; Curra, Anabella Paola; Carrillo, Elisa Cristina; Konig, Guido Alberto; Gismondi, Maria Ines (Oxford Academic Press, 2020-09)Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ... -
A computational study of the interaction of the foot and mouth disease virus VP1 with monoclonal antibodies
Marrero Diaz De Villegas, Rubén; Rodríguez Limardo, Ramiro; Carrillo, Elisa Cristina; Konig, Guido Alberto; Turjanski, Adrián G. (Elsevier, 2015-10)Foot and mouth disease is caused by a non-enveloped virus (FMDV), which disposes several antigenic sites at the surface of their capsid proteins. The most relevant and immunodominant antigenic site of FMDV (site A or AnSA) ... -
Cost-Effective Method to Perform SARS-CoV-2 Variant Surveillance: Detection of Alpha, Gamma, Lambda, Delta, Epsilon, and Zeta in Argentina
Torres, Carolina; Mojsiejczuk, Laura; Acuña, Dolores; Alexay, Sofía; Amadio, Ariel; Aulicino, Paula; Debat, Humberto Julio; Fay, Fabián; Fernandez, Franco Daniel; Giri, Adriana A.; Goya, Stephanie; Konig, Guido Alberto; Lucero, Horacio; Nabaes Jodar, Mercedes; Pianciola, Luis; Sfalcin, Javier A.; Acevedo, Raúl M.; Bengoa Luoni, Sofía Ailin; Bolatti, Elisa M.; Brusés, Bettina; Cacciabue, Marco Polo Domingo; Casal, Pablo E.; Cerri, Agustina; Chouhy, Diego; Dus Santos, Maria Jose; Eberhardt, María Florencia; Fernandez, Ailen; Fernandez, Paula Del Carmen; Fernández Do Porto, Darío; Formichelli, Laura; Gismondi, María Inés; Irazoqui, Jose Matias; Lorenzini Campos, Melina; Lusso, Silvina; Marquez, Nathalie; Muñoz Hidalgo, Marianne Graziel; Mussin, Javier; Natale, Mónica; Oria, Griselda; Pisano, María Belén; Posner, Victoria; Puebla, Andrea Fabiana; Viegas, Mariana (Frontiers Media, 2021-12-10)The emergence of SARS-CoV-2 variants with concerning characteristics to public health has attracted the attention of the scientific community and governments both regionally and globally since the end of 2020. The most ... -
Differences in the virulence of two strains of Foot-and-Mouth Disease Virus Serotype A with the same spatiotemporal distribution
Garcia Nuñez, Maria Soledad; Konig, Guido Alberto; Berinstein, Analia; Carrillo, Elisa Cristina (Elsevier, 2010-01)During the 2000–2001 epidemic of Foot-and-Mouth Disease Virus (FMDV) in Argentina, two FMDV serotype A viruses were identified among others. Since different pathogenic properties between these virus strains were noticed ... -
Identification and molecular characterization of Orf virus in Argentina
Peralta, Andrea Veronica; Robles, Carlos Alejandro; Martinez, Agustin; Alvarez, Lucia Paula; Valera, Alejandro; Calamante, Gabriela; Konig, Guido Alberto (Springer, 2015-06)Orf virus (ORFV) is the etiological agent of contagious ecthyma (CE), a pustular dermatitis of sheep and goats. Outbreaks of ORFV have been observed in all geographical regions of the world, including Argentina. The origin ... -
Molecular analyses detect natural coinfection of water buffaloes (Bubalus bubalis) with bovine viral diarrhea viruses (BVDV) in serologically negative animals = Detección molecular de coinfección con los virus de la diarrea viral bovina (BVDV) en búfalos de agua (Bubalus bubalis) serológicamente negativos
Craig, María Isabel; Konig, Guido Alberto; Benitez, Daniel Francisco; Draghi, Maria Graciela (Asociación Argentina de Microbiología, 2015)Infection of water buffaloes (Bubalus bubalis) with bovine viral diarrhea viruses (BVDV) has been confirmed in several studies by serological and molecular techniques. In order to determine the presence of persistently ... -
Molecular characterization and cluster analysis of field isolates of avian infectious laryngotracheitis virus from Argentina
Craig, María Isabel; Rojas, María Florencia; Van Der Ploeg, Claudia Andrea; Olivera, Valeria Soledad; Vagnozzi, Ariel Eduardo; Perez, Andrés M.; Konig, Guido Alberto (2017-12-13)Avian infectious laryngotracheitis (ILT) is a worldwide infectious disease that causes important economic losses in the poultry industry. Although it is known that ILT virus (ILTV) is present in Argentina, there is no ... -
Molecular characterization of infectious bursal disease virus (IBDV) isolated in Argentina indicates a regional lineage
Vera, Federico Sebastian; Craig, María Isabel; Olivera, Valeria Soledad; Rojas, María Florencia; Konig, Guido Alberto; Pereda, Ariel Julian; Vagnozzi, Ariel Eduardo (2015-08)In Argentina, classical vaccines are used to control infectious bursal disease virus (IBDV); however, outbreaks of IBDV are frequently observed. This could be due to failures in the vaccination programs or to the emergence ... -
Optimization and application of a high-resolution melting protocol in the characterization of avian infectious laryngotracheitis virus = Optimización y aplicación de un protocolo de desnaturalización de alta resolución en la caracterización del virus de la laringotraqueítis infecciosa aviar
Rojas, María Florencia; Konig, Guido Alberto; Vagnozzi, Ariel Eduardo; Vera, Federico Sebastian; Scolaro, Luis Alberto; Craig, María Isabel (Elsevier, 2020-09)A previous sequence analysis of a US5 gene fragment of infectious laryngotracheitis virus (ILTV) performed in an Argentinian epidemiological study allowed to differentiate between wild and vaccine strains. This analysis ... -
Phylogenetic analysis of ORF viruses from five contagious ecthyma outbreaks in Argentinian goats
Peralta, Andrea Veronica; Robles, Carlos Alejandro; Micheloud, Juan Francisco; Rossanigo, Carlos Esteban; Martinez, Agustin; Carosio, Agustin; Konig, Guido Alberto (2018-06)Orf virus (ORFV) is the etiological agent of Contagious Ecthyma (CE) disease that mainly affects sheep, goats, wild ruminants, and humans with a worldwide distribution. To date, only two strains from Argentinian sheep have ... -
Phylogeographic analysis of the 2000-2002 foot-and-mouth disease epidemic in Argentina
Brito, Barbara Patricia; Konig, Guido Alberto; Cabanne, Gustavo Sebastian; Perez Beascoechea, Claudia; Rodriguez, Luis; Perez, Andres (2016)Foot-and-mouth disease (FMD) is a highly transmissible disease of hooved livestock. Although FMD has been eradicated from many countries, economic and social consequences of FMD reintroductions are devastating. After ...