Now showing items 1-20 of 33

    • Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles 

      Bigi, María Mercedes; Vazquez, Cristina Lourdes; Castelão, Ana Beatriz C.; Garcia, Elizabeth Andrea; Cataldi, Angel Adrian; Jackson, Mary; McNeil, Michael; Soria, Marcelo Abel; Zumarraga, Martin Jose; Cabruja, Matias; Gago, Gabriela; Blanco, Federico Carlos; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Araujo, Flabio Ribeiro de; Bigi, Fabiana (Elsevier, 2019-12)
      Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ...
    • Association between spoligotype-VNTR types and virulence of Mycobacterium bovis in cattle 

      Garbaccio, Sergio Gabriel; Macias, Analía; Shimizu, Ernesto; Paolicchi, Fernando; Pezzone, Natalia; Zapata, Laura; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Peyru, Maite; Caimi, Karina Cynthia; Zumarraga, Martin Jose; Canal, Ana María; Cataldi, Angel Adrian; Magnano, Gabriel (Taylor & Francis, 2014-01)
      Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that affects approximately 5% of Argentine cattle. The aim of this research was to study if it is possible to infer the degree of virulence of ...
    • Bayesian assessment of the accuracy of a PCR-based rapid diagnostic test for bovine tuberculosis in swine 

      Barandiaran, Soledad; Perez Aguirreburualde, María Sol; Marfil, María Jimena; Martinez Vivot, Marcela; Aznar, Maria Natalia; Zumarraga, Martin Jose; Pérez, Andrés M. (Frontiers Media, 2019-06)
      Infection with the Mycobacterium bovis (M. bovis) causes a disease referred to as bovine tuberculosis (bTB), which affects a wide range of mammal hosts. Many countries have implemented control and eradication plans that ...
    • BoLA-DRB3 exon2 polymorphisms among tuberculous cattle: Nucleotide and functional variability and their association with bovine tuberculosis pathology 

      Eirin, Maria Emilia; Carignano, Hugo Adrian; Shimizu, Ernesto; Pando, Maria de los Angeles; Zumarraga, Martin Jose; Magnano, Gabriel; Macías, Analía; Garbaccio, Sergio Gabriel; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Ferrara Muñiz, Ximena; Cataldi, Angel Adrian; Paolicchi, Fernando; Poli, Mario Andres (Elsevier, 2020-06)
      Bovine tuberculosis (bTB) is caused by Mycobacterium bovis and disseminated worldwide. In Argentina, the highest prevalence occurs in dairy areas. BoLA DRB3.2 is related to the adaptive immunity in mycobacterial infections. ...
    • Bovine tuberculosis in domestic pigs: Genotyping and distribution of isolates in Argentina 

      Barandiaran, Soledad; Martinez Vivot, Marcela; Pérez, Andrés M.; Cataldi, Angel Adrian; Zumarraga, Martin Jose (Elsevier, 2015-12)
      Bovine tuberculosis is caused by Mycobacterium bovis and affects primarily cattle, among many other mammal species. In this study, 250 isolates of M. bovis collected from pigs slaughtered in Argentina were typed by ...
    • Detection of Mycobacterium bovis in Bovine and Bubaline tissues using Nested-PCR for TbD1 

      Araújo, Cristina Pires de; Osório, Ana Luiza Alves Rosa; Jorge, Klaudia dos Santos Goncalves; Ramos, Carlos Alberto N.; Filho, Antonio Francisco S.; Vidal, Carlos Eugênio Soto; Roxo, Eliana; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Júnior, Antônio A. F.; Silva, Marcio Roberto; Neto, Jose Diomedes Barbosa; Cerqueira, Valíria Duarte; Zumarraga, Martin Jose; Araujo, Flabio Ribeiro de (PLOS, 2014-03)
      In the present study, a nested-PCR system, targeting the TbD1 region, involving the performance of conventional PCR followed by real-time PCR, was developed to detect Mycobacterium bovis in bovine/bubaline tissue homogenates. ...
    • Detection of Mycobacterium bovis–infected dairy herds using PCR in bulk tank milk samples 

      Zumarraga, Martin Jose; Soutullo, Adriana; Garcia, Maria Ines; Marini, M. Rocío; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Echaide, Susana T. de; Lopez, Marcela; Zervini, Elsa; Canal, Ana María; Cataldi, Angel Adrian (Mary Ann Liebert Inc., 2012-02)
      Bovine tuberculosis (bTB) is a chronic and zoonotic disease due to Mycobacterium bovis. The tuberculosis eradication campaign carried out in Argentina has considerably improved the health situation of the herds. Here we ...
    • Diagnóstico bacteriológico de tuberculosis bovina en bovinos reactores positivos a la prueba tuberculínica 

      Garbaccio, Sergio Gabriel; Delgado, Fernando Oscar; Zumarraga, Martin Jose; Rodriguez, Liliana Rita; Huertas, Pablo Sebastian; Garro, Carlos Javier (2018-04)
      Mycobacterium bovis es el agente causal de la tuberculosis bovina (TBB), enfermedad zoonótica que afecta la producción láctea y cárnica. En nuestro país, el diagnóstico se realiza a través de la prueba tuberculínica o ...
    • Diversidad de especies de micobacterias no tuberculosas aisladas en ambientes acuáticos de la ciudad de General Pico, La Pampa, Argentina = Species diversity of non-tuberculous mycobacteria isolated from aquatic environments of General Pico city, Province of La Pampa (Argentina) 

      Tortone, Claudia Andrea; Oriani, Delia Susana; Staskevich, Ana Sandra; Oriani, Alejandra Soledad; Gino, Lilia Mabel; Marfil, Maria Jimena; Nava Vargas, Alejandro; Gioffre, Andrea; Zumarraga, Martin Jose (Asociación Argentina de Microbiología, 2018)
      Las micobacterias no tuberculosas (MNT) no solo se estudian por su importancia como patógenos oportunistas, sino también por sus aplicaciones en biotecnología y biorremediación. Nuestro objetivo fue determinar la presencia ...
    • Draft genome sequence of Mycobacterium bovis 04-303, a highly virulent strain from Argentina 

      Nishibe, Christiane; Canevari Castelão, Ana Beatriz; Dalla Costa, Ricardo; Pinto, Beatriz Jeronimo; Varuzza, Leonardo; Cataldi, Angel Adrian; Bernardelli, Amelia; Bigi, Fabiana; Blanco, Federico Carlos; Zumarraga, Martin Jose; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de (American Society for Microbiology, 2013-11)
      Mycobacterium bovis strain 04-303 was isolated from a wild boar living in a free-ranging field in Argentina. This work reports the draft genome sequence of this highly virulent strain and the genomic comparison of its major ...
    • Draft genome sequences of two mycobacterium bovis strains isolated from beef cattle in Paraguay 

      Sanabria, Lidia; Lagrave, Lorena; Nishibe, Christiane; Ribas, Augusto C.A.; Zumarraga, Martin Jose; Almeida, Nalvo F.; Araujo, Flabio Ribeiro de (2017-07)
      This work reports the draft genome sequences of the Mycobacterium bovis strains M1009 and M1010, isolated from the lymph nodes of two infected cows on a beef farm in Paraguay. Comparative genomics between these strains and ...
    • Enzyme-linked immunosorbent assay as complement of intradermal skin test for the detection of mycobacterium bovis infection in cattle 

      Garbaccio, Sergio Gabriel; Garro, Carlos Javier; Delgado, Fernando Oscar; Tejada, G. A.; Eirin, Maria Emilia; Huertas, Pablo Sebastian; Leon, Emilio Arnaldo; Zumarraga, Martin Jose (Elsevier, 2019-07)
      Diagnostic tests based on cell-mediated immunity are used in programs for the control and eradication of bovine tuberculosis (bTB), which is mainly caused by Mycobacterium bovis. Additional serological assays could be ...
    • Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts 

      Morcillo, Nora; Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Zumarraga, Martin Jose; Takif, Howard; Cataldi, Angel Adrian (Elsevier, 2014-12)
      There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this ...
    • Genotyping Mycobacterium bovis from cattle in the Central Pampas of Argentina: tempoal and regional trends 

      Shimizu, Ernesto; Macias, Analía; Paolicchi, Fernando; Magnano, Gabriel; Zapata, Laura; Fernandez, Analía; Canal, Ana María; Garbaccio, Sergio Gabriel; Cataldi, Angel Adrian; Caimi, Karina Cynthia; Zumarraga, Martin Jose (Fundacao Oswaldo Cruz, Brasil, 2014-04)
      Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a disease that affects approximately 5% of Argentinean cattle. Among the molecular methods for genotyping, the most convenient are spoligotyping and ...
    • La genómica de las micobacterias 

      Viale, Mariana; Zumarraga, Martin Jose; Araujo, Flabio Ribeiro de; Zarraga, Ana Maria; Cataldi, Angel Adrian; Romano, Maria Isabel; Bigi, Fabiana (Office International des Epizooties, 2016)
      Las especies Mycobacterium bovis y Mycobacterium avium subsp. paratuberculosis son los agentes causales de la tuberculosis y la paratuberculosis en animales, respectivamente. Además, ambas micobacterias, pero fundamentalmente ...
    • Immunohistochemical detection of pro-inflammatory and anti-inflammatory cytokines in granulomas in cattle with natural Mycobacterium bovis infection 

      Canal, Ana María; Pezzone, Natalia; Cataldi, Angel Adrian; Zumarraga, Martin Jose; Larzabal, Mariano; Garbaccio, Sergio Gabriel; Fernández, Analía; Dominguez, Lucas; Aranaz, Alicia; Rodriguez-Bertos, Antonio (2017)
      Cellular immune response was evaluated in lymph nodes and lung with different granulomatous lesions from cattle naturally infected with Mycobacterium bovis. For this purpose, we assessed pro-inflammatory and anti-inflamm ...
    • LAMP technology: Rapid identification of Brucella and Mycobacterium avium subsp. paratuberculosis 

      Trangoni, Marcos David; Gioffre, Andrea; Ceron Cucchi, Maria Esperanza; Caimi, Karina Cynthia; Ruybal, Paula; Zumarraga, Martin Jose; Cravero, Silvio Lorenzo Pedro (Sociedade Brasileira de Microbiologia, 2015-06)
      In this study, we developed new sets of primers to detect Brucella spp. and M. avium subsp. paratuberculosis (MAP) through isothermal amplification. We selected a previously well-characterized target gene, bscp31, specific ...
    • Matrix assisted laser desorption ionization-time-of-flight mass spectrometry identification of mycobacterium bovis in bovinae 

      Bacanelli, Gisele; Olarte, Larissa C.; Silva, Marcio Roberto; Rodrigues, Rudielle A.; Carneiro, Paulo A. M.; Kannene, John B.; Pasquatti, Taynara N.; Takatani, Haruo; Zumarraga, Martin Jose; Etges, Rodrigo N.; Araujo, Flabio Ribeiro de; Verbisck, Newton V. (The Japanese Society of Veterinary Science, 2019-10)
      In this study, Matrix Assisted Laser Desorption Ionization-Time-of-Flight (MALDI-TOF) mass spectrometry was used to identify Mycobacterium bovis from cattle and buffalo tissue isolates from the North and South regions of ...
    • Mycobacterioses in dogs and cats from Buenos Aires, Argentina 

      Barandiaran, Soledad; Martinez Vivot, Marcela; Falzoni, Elvira; Marfil, Maria Jimena; Perez Tort, Gabriela; Rovatti, Paula; Fernandez, Mónica; Iachini, Ricardo; Satek, Fernanda; Duchene, Adriana; Zumarraga, Martin Jose (Sage Publications, 2017-09)
      Mycobacterioses can produce nonspecific clinical signs in dogs and cats that make diagnosis difficult. Furthermore, the full characterization of mycobacterial agents is not always possible or practical. We characterized ...
    • Mycobacterium bovis en fauna silvestre de la cuenca lechera de Santa Fe, Argentina = Mycobacterium bovis in wildlife of the dairy regions of Santa Fe (Argentina) 

      Abdala, Alejandro Ariel; Garbaccio, Sergio Gabriel; Zumarraga, Martin Jose; Tarabla, Hector Dante (2015-09)
      El control y la erradicación de la tuberculosis bovina basados en la detección de los animales infectados y su inmediata faena permitió lograr progresos satisfactorios en varios países y regiones, pero no todos pudieron ...