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Mostrando ítems 61-80 de 375

    • Pre-columbian mycobacterial genomes reveal seals as a source of new world human tuberculosis 

      Bos, Kirsten I.; Harkins, Kelly M.; Herbig, Alexander; Coscolla, Mireia; Weber, Nico; Comas, Iñaki; Forrest, Stephen A.; Bryant, Josephine M.; Harris, Simon R.; Schuenemann, Verena J.; Campbell, Tessa J.; Majander, Kerrtu; Wilbur, Alicia K.; Guichon, Ricardo A.; Steadman, Dawnie L. Wolfe; Cook, Della Collins; Niemann, Stefan; Behr, Marcel A.; Zumarraga, Martin Jose; Bastida, Ricardo; Huson, Daniel; Nieselt, Kay; Young, Douglas; Parkhill, Julian; Buikstra, Jane E.; Gagneux, Sebastien; Stone, Anne C.; Krause, Johannes (Springer Nature, 2014-08)
      Modern strains of Mycobacterium tuberculosis from the Americas are closely related to those from Europe, supporting the assumption that human tuberculosis was introduced post-contact1. This notion, however, is incompatible ...

    • Experimental selection of long‐term intracellular mycobacteria 

      Vazquez, Cristina Lourdes; Lerner, Thomas R.; Kasmapour, Bahram; Pei, Gang; Gronow, Achim; Bianco, María Veronica; Blanco, Federico Carlos; Bleck, Christopher K.E.; Geffers, Robert; Bigi, Fabiana; Abraham, Wolf-Rainer; Gutierrez, Maximiliano Gabriel (Wiley, 2014-09)
      Some intracellular bacteria are known to cause long‐term infections that last decades without compromising the viability of the host. Although of critical importance, the adaptations that intracellular bacteria undergo ...

    • The genome of the stress-tolerant wild tomato species Solanum pennellii 

      Bolger, Anthony; Scossa, Federico; Bolger, Marie E.; Lanz, Christa; Maumus, Florian; Tohge, Takayuki; Quesneville, Hadi; Alseekh, Saleh; Sørensen, Iben; Lichtenstein, Gabriel; Fich, Eric A.; Conte, Mariana; Keller, Heike; Schneeberger, Korbinian; Schwacke, Rainer; Ofner, Itai; Vrebalov, Julia; Xu, Yimin; Osorio, Sonia; Aflitos, Saulo Alves; Schijlen, Elio; Jiménez-Goméz, José M.; Ryngajllo, Malgorzata; Kimura, Seisuke; Kumar, Ravi; Koenig, Daniel; Headland, Lauren R.; Maloof, Julin N.; Sinha, Neelima; van Ham, Roeland C. H. J.; Lankhorst, René Klein; Mao, Linyong; Vogel, Alexander; Arsova, Borjana; Panstruga, Ralph; Fei, Zhangjun; Rose, Jocelyn K. C.; Zamir, Dani; Carrari, Fernando; Giovannoni, James J.; Weigel, Detlef; Usadel, Björn; Fernie, Alisdair R. (Nature Publishing Group, 2014-09)
      Solanum pennellii is a wild tomato species endemic to Andean regions in South America, where it has evolved to thrive in arid habitats. Because of its extreme stress tolerance and unusual morphology, it is an important ...

    • Tomato Abscisic Acid Stress ripening (ASR) gene family revisited 

      Golan, Ido; Dominguez, Pia Guadalupe; Konrad, Zvia; Shkolnik Inbar, Doron; Carrari, Fernando; Bar Zvi, Dudy (PLOS, 2014-10-13)
      Tomato ABSCISIC ACID RIPENING 1 (ASR1) was the first cloned plant ASR gene. ASR orthologs were then cloned from a large number of monocot, dicot and gymnosperm plants, where they are mostly involved in response to abiotic ...

    • Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens 

      Molinari, Maria Paula; Peralta, Andrea Veronica; Maletto, Belkys Angélica; Pistoresi Palencia, Maria Cristina; Crespo, Maria Ines; Moron, Victor Gabriel; Taboga, Oscar Alberto (Elsevier, 2014-11)
      The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ...

    • IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis 

      Rovetta, Ana Inés; Peña, Delfina; Hernández del Pino, Rodrigo Emanuel; Recalde, Gabriela María; Pellegrini, Joaquín Miguel; Bigi, Fabiana; Musella, Rosa María; Palmero, Domingo; Gutierrez, Marisa; Colombo, Maria Isabel; García, Verónica Edith (Taylor & Francis, 2014-11)
      Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of ...

    • Lipoxygenase activation in peanut seed cultivars resistant and susceptible to Aspergillus parasiticus colonization 

      Muller, Virginia; Amé, María Valeria; Carrari, Fernando; Gieco, Jorge Omar; Asis, Ramón (American Phytopathological Society, 2014-12)
      Accumulative evidence indicates that the lipoxygenase (LOX) pathway plays a significant role in the Aspergillus–seed interaction, such as interfering with activities of endogenous fungal oxylipins or producing antimicrobial ...

    • Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts 

      Morcillo, Nora; Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Zumarraga, Martin Jose; Takif, Howard; Cataldi, Angel Adrian (Elsevier, 2014-12)
      There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this ...

    • An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum 

      Veluchamy, Alaguraj; Rastogi, Achal; Lin, Xin; Lombard, Bérangère; Murik, Omer; Thomas, Yann; Dingli, Florent; Rivarola, Maximo Lisandro; Ott, Sandra; Liu, Xinyue; Sun, Yezhou; Rabinowicz, Pablo D.; McCarthy, James; Allen, Andrew E.; Loew, Damarys; Bowler, Chris; Tirichine, Leïla (BioMed Central, 2015)
      Background: Nucleosomes are the building blocks of chromatin where gene regulation takes place. Chromatin landscapes have been profiled for several species, providing insights into the fundamental mechanisms of ...

    • Population structure and genetic diversity characterization of a sunflower association mapping population using SSR and SNP markers 

      Filippi, Carla Valeria; Aguirre, Natalia Cristina; Rivas, Juan Gabriel; Zubrzycki, Jeremias Enrique; Puebla, Andrea Fabiana; Cordes, Diego Darío; Moreno, Maria Valeria; Fusari, Corina Mariana; Alvarez, Daniel; Heinz, Ruth Amelia; Hopp, Horacio Esteban; Paniego, Norma Beatriz; Lia, Veronica Viviana (BMC, 2015-02)
      Background: Argentina has a long tradition of sunflower breeding, and its germplasm is a valuable genetic resource worldwide. However, knowledge of the genetic constitution and variability levels of the Argentinean germplasm ...

    • ASR1 transcription factor and its role in metabolism 

      Dominguez, Pia Guadalupe; Carrari, Fernando (Taylor & Francis, 2015-03)
      Asr1 (ABA, stress, ripening) is a plant gene widely distributed in many species which was discovered by differential induction levels in tomato plants subjected to drought stress conditions. ASR1 also regulates the expression ...

    • Estrategia de inmunoprofilaxis para la prevención de la rabia paresiante utilizando un virus canarypox recombinante = Immunoprophylaxis strategy for the prevention of paralytic rabies using a recombinant canarypox virus 

      Garanzini, Debora Patricia; Rossner, Maria Victoria; Stahringer, Rodolfo Carlos; Micucci, Matías; Perez, Oscar; Del Medico Zajac, Maria Paula; Russo, Susana; Calamante, Gabriela (Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA), 2015-03)
      La rabia paresiante es una enfermedad causada por el virus rábico transmitido por el vampiro común. En el norte de nuestro país, se registran anualmente un número limitado de casos por lo que es necesaria la implementación ...

    • Mycobacterium bovis infection in a horse with granulomatous enterocolitis 

      Sarradell, Javier E.; Alvarez, Julio; Biscia, Mariana; Zumarraga, Martin Jose; Wunschmann, Arno; Armien, Aníbal G.; Perez, Andrés M. (Sage Publications, 2015-03)
      A 2-year-old dappled Percheron horse had a wasting condition that did not respond to antibiotic treatments and ultimately resulted in death. Thickening of the wall of the large colon and enlargement of the mesenteric lymph ...

    • Development of a Multilocus Sequence Typing scheme for the study of Anaplasma marginale population structure over space and time 

      Guillemi, Eliana Carolina; Ruybal, Paula; Lia, Veronica Viviana; Gonzalez, Sergio Alberto; Lew, Sergio Eduardo; Zimmer, Patricia Andrea; Lopez Arias, Ludmila Sol; Rodríguez, José Luis; Rodriguez, Sonia Y.; Frutos, Roger; Wilkowsky, Silvina Elizabeth; Farber, Marisa Diana (Elsevier, 2015-03)
      Bovine Anaplasmosis caused by Anaplasma marginale is a worldwide disease prevalent in tropical and subtropical regions where Rhipicephalus microplus is considered the most significant biological vector. Molecular markers ...

    • Tuberculosis in swine co-infected with Mycobacterium avium subsp. hominissuis and Mycobacterium bovis in a cluster from Argentina 

      Barandiaran, Soledad; Pérez, Andrés M.; Gioffre, Andrea; Martinez Vivot, Marcela; Cataldi, Angel Adrian; Zumarraga, Martin Jose (Cambridge University Press, 2015-04)
      In Argentina little is known about the epidemiology of tuberculosis (TB) infection in swine. We characterized the epidemiological dynamics of Mycobacterium avium complex (MAC) infection in a swine population of Argentina ...

    • In vivo short-term exposure to residual oil fly ash impairs pulmonary innate immune response against environmental mycobacterium infection 

      Delfosse, Veronica Cecilia; Tasat, Deborah Ruth; Gioffre, Andrea (Wiley, 2015-05)
      Epidemiological studies have shown that pollution derived from industrial and vehicular transportation induces adverse health effects causing broad ambient respiratory diseases. Therefore, air pollution should be taken ...

    • LAMP technology: Rapid identification of Brucella and Mycobacterium avium subsp. paratuberculosis 

      Trangoni, Marcos David; Gioffre, Andrea; Ceron Cucchi, Maria Esperanza; Caimi, Karina Cynthia; Ruybal, Paula; Zumarraga, Martin Jose; Cravero, Silvio Lorenzo Pedro (Sociedade Brasileira de Microbiologia, 2015-06)
      In this study, we developed new sets of primers to detect Brucella spp. and M. avium subsp. paratuberculosis (MAP) through isothermal amplification. We selected a previously well-characterized target gene, bscp31, specific ...

    • Clade 8 and clade 6 strains of Escherichia coli O157:H7 from cattle in Argentina have Hypervirulent-Like phenotypes 

      Amigo, Natalia; Mercado, Elsa Cristina; Bentancor, Adriana Beatriz; Singh, Pallavi; Vilte, Daniel Alejandro; Gerhardt, Elizabeth; Zotta, Elsa; Ibarra, Cristina Adriana; Manning, Shannon D.; Larzabal, Mariano; Cataldi, Angel Adrian (PLOS, 2015-06-01)
      The hemolytic uremic syndrome (HUS) whose main causative agent is enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a disease that mainly affects children under 5 years of age. Argentina is the country with the highest ...

    • Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level 

      Zavallo, Diego; Debat, Humberto Julio; Conti, Gabriela; Manacorda, Carlos Augusto; Rodriguez, Maria Cecilia; Asurmendi, Sebastian (2015-08-03)
      Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional ...

    • Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein 

      Carballeda, Juan Manuel; Maroniche, Guillermo Andrés; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (Elsevier, 2015-09)
      Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ...