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Mostrando ítems 1-9 de 9

    • A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity 

      Salmen, Wilhelm; Hu, Liya; Bok, Marina; Chaimongkol, Natthawan; Ettayebi, Khalil; Sosnovtsev, Stanislav V.; Soni, Kaundal; Ayyar, B. Vijayalakshmi; Shanker, Sreejesh; Neill, Frederick H.; Sankaran, Banumathi; Atmar, Robert L.; Estes, Mary K.; Green, Kim Y.; Parreño, Gladys Viviana; Prasad, B. V. Venkataram (Nature Publishing Group, 2023-10)
      Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus ...

    • Development of an IgY-Based treatment to control bovine Coronavirus diarrhea in dairy calves 

      Bok, Marina; Vega, Celina Guadalupe; Castells, Matias; Colina, Rodney; Wigdorovitz, Andres; Parreño, Gladys Viviana (MDPI, 2023-03)
      Bovine Coronavirus (BCoV) is a major pathogen associated with neonatal calf diarrhea. Standard practice dictates that to prevent BCoV diarrhea, dams should be immunized in the last stage of pregnancy to increase BCoV-specific ...

    • Development of nanobody-displayed whole-cell biosensors for the colorimetric detection of SARS-CoV‑2 

      He, Yawen; Xu, Zhiyuan; Kasputis, Tom; Zhao, Xue; Ibañez, Itati; Pavan, Florencia; Bok, Marina; Malito, Juan Pablo; Parreño, Gladys Viviana; Yuan, Lijuan; Wright, R. Clay; Chen, Juhong (American Chemical Society, 2023-08)
      The accurate and effective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to preventing the spread of infectious diseases and ensuring human health. Herein, a nanobody-displayed ...

    • Molecular and antigenic characterization of bovine Coronavirus circulating in Argentinean cattle during 1994–2010 

      Bok, Marina; Miño, Samuel; Rodriguez, Daniela; Badaracco, Alejandra; Nuñes, I.; Souza, Sibele P.; Bilbao, G.; Louge Uriarte, Enrique Leopoldo; Galarza, Roxana Ivon; Vega, Celina Guadalupe; Odeon, Anselmo Carlos; Saif, LInda J.; Parreño, Gladys Viviana (Elsevier, 2015-12)
      Bovine coronavirus (BCoV) is an important viral pathogen associated with neonatal calf diarrhea. Our aim was to investigate the incidence of BCoV in diarrhea outbreaks in beef and dairy herds from Argentina during 1994–2010. ...

    • Molecular characterization of group A rotavirus strains detected in alpacas (Vicugna pacos) from Peru 

      Badaracco, Alejandra; Cordero, Aida; Vega, Celina Guadalupe; Bok, Marina; Zeller, Mark; Heylen, Elisabeth; Fernández, Gonzalo; Díez-Baños, Pablo; Morrondo, Patrocinio; Guevara, Héctor; Matthijnssens, Jelle; Parreño, Gladys Viviana (Microbiology Society, 2021-04)
      The alpaca is a very important social and economic resource for the production of fibre and meat for Andean communities. Peru is the main producer of alpacas. Group A rotavirus (RVA) has been sporadically detected in ...

    • Molecular detection of bovine Noroviruses in Argentinean dairy calves : circulation of a tentative new genotype 

      Ferragut, Fátima; Vega, Celina Guadalupe; Mauroy, Axel; Conceição-Neto, Nádia; Zeller, Mark; Heylen, Elisabeth; Louge Uriarte, Enrique Leopoldo; Bilbao, Gladys; Bok, Marina; Matthijnssens, Jelle; Thiry, Etienne; Badaracco, Alejandra; Parreño, Gladys Viviana (2016)
      Bovine noroviruses are enteric pathogens detected in fecal samples of both diarrheic and non-diarrheic calves from several countries worldwide. However, epidemiological information regarding bovine noroviruses is still ...

    • Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus 

      Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen II, D. Lee; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina Guadalupe; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreño, Gladys; Love, Kerry R.; Love, J. Christopher (BMC, 2021-05)
      Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ...

    • Passive immunity to control Bovine coronavirus diarrhea in a dairy herd in Argentina = Inmunidad pasiva en el control de la diarrea por coronavirus bovino en un rodeo lechero de Argentina 

      Bok, Marina; Alassia, Martín; Frank, Flavia; Vega, Celina Guadalupe; Wigdorovitz, Andres; Parreño, Viviana (2018)
      Bovine coronavirus (BCoV) is a viral enteric pathogen associated with calf diarrhea worldwide being, in Argentina, mostly detected in dairy husbandry systems. The aim of the present work was to study if maternal IgG1 ...

    • Prevalence and viability of group A rotavirus in dairy farm water sources 

      Castells, M.L.; Schild, Carlos Omar; Caffarena, Rubén Dario; Bok, Marina; Giannitti, Federico; Armendano, Joaquín Ignacio; Riet‐Correa, Franklin; Victoria, M.; Parreño, Viviana; Colina, Rodney (2018-03)
      Aim: To analyse group A rotavirus (RVA) environmental contamination in waters used for calves' consumption and to assess viral viability in dairy farm water sources. Methods and Results: We analysed 202 samples of water ...