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    • Clostridium perfringens epsilon toxin induces permanent neuronal degeneration and behavioral changes 

      Morris, Winston Eduardo; Goldstein, Jorge; Redondo, Leandro Martí­n; Cangelosi, Adriana; Geoghegan, Patricia; Brocco, Marcela Adriana; Loidl, Fabián C.; Fernandez Miyakawa, Mariano Enrique (2017-05)
      Clostridium perfringens epsilon toxin (ETX), the most potent toxin produced by this bacteria, plays a key role in the pathogenesis of enterotoxaemia in ruminants, causing brain edema and encephalomalacia. Studies of animals ...

    • Effects of Clostridium perfringens iota toxin in the small intestine of mice 

      Redondo, Leandro Martin; Redondo, Enzo Alejandro; Dailoff, Gabriela Cecilia; Leiva, Carlos; Diaz Carrasco, Juan Maria; Bruzzone, Octavio Augusto; Cangelosi, Adriana; Geoghegan, Patricia; Fernandez Miyakawa, Mariano Enrique (2017-12)
      Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme. As type E causes hemorrhagic enteritis in cattle, it ...

    • Rol de las toxinas binarias en las enfermedades intestinales causadas por clostridios enterotóxicos 

      Redondo, Leandro Martín (Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-03)
      Las enfermedades digestivas causadas por especies del genero Clostridium poseen un importante impacto en la medicina tanto humana como veterinaria. Entre las especies patógenas más importantes de este género se encuentran ...