Mostrar el registro sencillo del ítem
resumen
Resumen
Nontuberculous mycobacteria (NTM) lung infections are often misdiagnosed as tuberculosis, which can lead to ineffective antibiotic treatments. In this report, we present three cases of NTM lung infections in Ecuador that were initially diagnosed and treated as tuberculosis based on the results of sputum smear microscopy. The patients, all male, included two immunocompetent individuals and one HIV-positive subject. Unfortunately, sputum culture was not
[ver mas...]
dc.contributor.author | Echeverria, Gustavo | |
dc.contributor.author | Rueda, Veronica | |
dc.contributor.author | Espinoza, Wilson | |
dc.contributor.author | Rosero, Carlos | |
dc.contributor.author | Zumarraga, Martin Jose | |
dc.contributor.author | Waard, Jacobus H. de | |
dc.coverage.spatial | Ecuador .......... (nation) (World, South America) | es_AR |
dc.coverage.spatial | 1000051 | es_AR |
dc.date.accessioned | 2023-04-12T16:31:59Z | |
dc.date.available | 2023-04-12T16:31:59Z | |
dc.date.issued | 2023-04 | |
dc.identifier.issn | 2076-0817 | |
dc.identifier.other | https://doi.org/10.3390/pathogens12040507 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12123/14457 | |
dc.identifier.uri | https://www.mdpi.com/2076-0817/12/4/507 | |
dc.description.abstract | Nontuberculous mycobacteria (NTM) lung infections are often misdiagnosed as tuberculosis, which can lead to ineffective antibiotic treatments. In this report, we present three cases of NTM lung infections in Ecuador that were initially diagnosed and treated as tuberculosis based on the results of sputum smear microscopy. The patients, all male, included two immunocompetent individuals and one HIV-positive subject. Unfortunately, sputum culture was not initiated until late in the course of the disease and the cause of the lung infection, Mycobacterium avium complex (MAC), was only identified after the patients had either passed away or were lost to follow-up. These cases are the first documented cases of NTM lung infections in the English medical literature from Ecuador. We emphasize the importance of accurate diagnosis of NTM infections by culture and identification to species level. Sputum smear staining alone cannot differentiate between mycobacterial species, which can lead to misidentification and ineffective treatments. Additionally, reporting NTM pulmonary disease as a notifiable disease to national TB control programs is recommended to obtain accurate prevalence data. These data are critical in determining the importance of this public health problem and the necessary actions needed to address it. | eng |
dc.format | application/pdf | es_AR |
dc.language.iso | eng | es_AR |
dc.publisher | MDPI | es_AR |
dc.rights | info:eu-repo/semantics/openAccess | es_AR |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | es_AR |
dc.source | Pathogens 12 (4) : 507. (April 2023) | es_AR |
dc.subject | Mycobacterium | es_AR |
dc.subject | Enfermedades Pulmonares | es_AR |
dc.subject | Pulmonary Diseases | eng |
dc.subject | Tuberculosis | eng |
dc.subject | Diagnóstico | es_AR |
dc.subject | Diagnosis | eng |
dc.subject | Ecuador | es_AR |
dc.subject.other | Nontuberculous Mycobacteria | es_AR |
dc.title | First Case Reports of Nontuberculous Mycobacterial (NTM) Lung Disease in Ecuador: Important Lessons to Learn | es_AR |
dc.type | info:ar-repo/semantics/artículo | es_AR |
dc.type | info:eu-repo/semantics/article | es_AR |
dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
dc.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | es_AR |
dc.description.origen | Instituto de Biotecnología | es_AR |
dc.description.fil | Fil: Echeverria, Gustavo. Universidad Central del Ecuador. Instituto de Investigación en Zoonosis-CIZ; Ecuador | es_AR |
dc.description.fil | Fil: Echeverria, Gustavo. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Programa de Doctorado; Argentina | es_AR |
dc.description.fil | Fil: Echeverria, Gustavo. BioGENA. División Investigación y Desarrollo; Ecuador | es_AR |
dc.description.fil | Fil: Rueda, Veronica. Universidad Central del Ecuador. Instituto de Investigación en Zoonosis-CIZ; Ecuador | es_AR |
dc.description.fil | Fil: Espinoza, Wilson. Hospital de Especialidades Eugenio Espejo. Departamento de Tuberculosis; Ecuador | es_AR |
dc.description.fil | Fil: Rosero, Carlos. Hospital de Especialidades Eugenio Espejo. Departamento de Tuberculosis; Ecuador | es_AR |
dc.description.fil | Fil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina | es_AR |
dc.description.fil | Fil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina | es_AR |
dc.description.fil | Fil: Waard, Jacobus H. de. Universidad Central de Venezuela. Instituto de Biomedicina “Jacinto Convit”. Departamento de Tuberculosis; Venezuela | es_AR |
dc.description.fil | Fil: Waard, Jacobus H. de. Universidad de Las Américas. Facultad de Ciencias de la Salud. One Health Research Group; Ecuador | es_AR |
dc.subtype | cientifico |
Ficheros en el ítem
Este ítem aparece en la(s) siguiente(s) colección(ones)
common
-
Artículos científicos [375]