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Resumen
Bovine viral diarrhea virus (BVDV) is an important pathogen of ruminants worldwide and is characterized by high genetic diversity and a wide range of clinical presentations. In Argentina, several studies have evaluated the genetic diversity of BVDV but no phylodynamic study has been published yet. In this study, a comprehensive compilation and update of Argentinean BVDV sequences were performed, and the evolutionary history of BVDV was characterized by
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dc.contributor.author | Spetter, Lucas Maximiliano | |
dc.contributor.author | Louge Uriarte, Enrique Leopoldo | |
dc.contributor.author | Verna, Andrea Elizabeth | |
dc.contributor.author | Leunda, Maria Rosa | |
dc.contributor.author | Pereyra, Susana Beatriz | |
dc.contributor.author | Odeon, Anselmo Carlos | |
dc.contributor.author | Gonzalez Altamiranda, Erika | |
dc.date.accessioned | 2022-10-03T17:09:44Z | |
dc.date.available | 2022-10-03T17:09:44Z | |
dc.date.issued | 2021-12 | |
dc.identifier.issn | 1567-1348 | |
dc.identifier.other | https://doi.org/10.1016/j.meegid.2021.105089 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12123/13031 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S1567134821003877 | |
dc.description.abstract | Bovine viral diarrhea virus (BVDV) is an important pathogen of ruminants worldwide and is characterized by high genetic diversity and a wide range of clinical presentations. In Argentina, several studies have evaluated the genetic diversity of BVDV but no phylodynamic study has been published yet. In this study, a comprehensive compilation and update of Argentinean BVDV sequences were performed, and the evolutionary history of BVDV was characterized by phylodynamic analyses based on the 5´UTR. Although BVDV-1b and BVDV-1a were the most frequent subtypes, novel subtypes for Argentina, 1e and 1i, were identified. The phylodynamic analysis suggested that BVDV started its diversification in the mid-1650s with an exponential increase in viral diversity since the late 1990s, possibly related to the livestock expansion and intensification in the country. Evolutionary rate in the 5´UTR was faster for BVDV-1a than for BVDV-1b, and both subtypes presented an endemic nature according to the demographic reconstructions. The current study contributes to clarify the evolutionary history of BVDV in the main cattle region of the country and provides useful information about the epidemiology and future development of diagnostic and control tools in Argentina. | eng |
dc.format | application/pdf | es_AR |
dc.language.iso | eng | es_AR |
dc.publisher | Elsevier | es_AR |
dc.relation | info:eu-repograntAgreement/INTA/PNSA-1115053/AR./Biotecnologías reproductivas y desarrollo de metodologías de diagnóstico, control y prevención de las enfermedades infecciosas y parasitarias que afectan la concepción, gestación y período neonatal en especies de interés zootécnico. | es_AR |
dc.rights | info:eu-repo/semantics/restrictedAccess | es_AR |
dc.source | Infection, Genetics and Evolution 96 : 105089 (December 2021) | es_AR |
dc.subject | Diarrea Viral Bovina | es_AR |
dc.subject | Bovine Viral Diarrhoea | eng |
dc.subject | Rumiante | es_AR |
dc.subject | Ruminants | eng |
dc.subject | Análisis Filogenético | es_AR |
dc.subject | Phylogenetic Analysis | eng |
dc.subject | Filogenia | es_AR |
dc.subject | Phylogeny | eng |
dc.subject | Argentina | es_AR |
dc.title | Genomic diversity and phylodynamic of bovine viral diarrhea virus in Argentina | es_AR |
dc.type | info:ar-repo/semantics/artículo | es_AR |
dc.type | info:eu-repo/semantics/article | es_AR |
dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
dc.description.origen | EEA Balcarce | es_AR |
dc.description.fil | Fil: Spetter, Maximiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.description.fil | Fil: Louge Uriarte, Enrique Leopoldo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.description.fil | Fil: Verna, Andrea Elizabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.description.fil | Fil: Leunda, María Rosa. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.description.fil | Fil: Pereyra, Susana Betriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.description.fil | Fil: Odeón, Anselmo Carlos. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina. | es_AR |
dc.description.fil | Fil: González Altamiranda, Erika. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. | es_AR |
dc.subtype | cientifico |
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