Mostrar el registro sencillo del ítem

resumen

Resumen
Background: Neonatal calf diarrhea (NCD) is the leading cause of calf morbidity and mortality in beef cattle. Cow’s vaccination in last stage of pregnancy is one of the most important measures to mitigate the risk of NCD outbreaks. The aim of this study was to evaluate the efficacy of prepartum single dose vaccination against NCD, especially Bovine Rotavirus type A (BoRVA) and Bovine Coronavirus (BCoV), in Nelore dams and offspring. A total of 117 [ver mas...]
dc.contributor.authorPinheiro, Filipe Aguera
dc.contributor.authorDecaris, Nathália
dc.contributor.authorParreño, Gladys Viviana
dc.contributor.authorBrandão, Paulo Eduardo
dc.contributor.authorAyres, Henderson
dc.contributor.authorGomes, Viviani
dc.date.accessioned2022-08-29T10:23:21Z
dc.date.available2022-08-29T10:23:21Z
dc.date.issued2022-08
dc.identifier.issn1746-6148
dc.identifier.otherhttps://doi.org/10.1186/s12917-022-03391-5
dc.identifier.urihttp://hdl.handle.net/20.500.12123/12708
dc.identifier.urihttps://bmcvetres.biomedcentral.com/articles/10.1186/s12917-022-03391-5
dc.description.abstractBackground: Neonatal calf diarrhea (NCD) is the leading cause of calf morbidity and mortality in beef cattle. Cow’s vaccination in last stage of pregnancy is one of the most important measures to mitigate the risk of NCD outbreaks. The aim of this study was to evaluate the efficacy of prepartum single dose vaccination against NCD, especially Bovine Rotavirus type A (BoRVA) and Bovine Coronavirus (BCoV), in Nelore dams and offspring. A total of 117 pregnant cows (n = 81) and heifers (n = 36) were distributed in two groups, vaccinated (VAC: cows = 40; heifers = 19) and nonvaccinated (NVAC: cows = 41; heifers = 17). Vaccination occurred between 60 to 50 days before the expected calving date with a single dose of a water-in-oil (W/O) vaccine, and NVAC group received a dose of saline solution 0.9%. Blood samples were collected before vaccination and 30 days after to evaluate the antibody (Ab) response. Specific IgG1 Abs against BoRVA and BCoV were measured by using an Enzyme Linked Immuno Sorbent Assay (ELISA). Calves’ births were monitored, and the transference of passive immunity was evaluated. Diarrhea was monitored in the first 30 days of age, and fecal samples were collected for identification of the etiological agent. Results: Higher titers of IgG1 Ab against BoRVA and BCoV was observed in the VAC group than NVAC group in the cow (P < 0.0001) and total dams categories (P < 0.0001). The titer of specific IgG1 Abs in the calves’ serum reflected the dams response, observing higher IgG1 Ab titers for BoRVA (P < 0.0016) and BCoV (P < 0.0095) in the offspring born to VAC cows and higher IgG1 Ab titers for BoRVA(P < 0.0171) and BCoV (P < 0.0200) in the offspring born to VAC total dams. The general incidence of diarrhea observed was 18.6% (11/59) and 29.3% (17/58) in the calves born to the VAC and NVAC group, respectively. Conclusions: Prepartum vaccination with a single dose of the vaccine tested increased the titers of IgG1 Ab against BCoV and BoRVA, and it could be used as a preventive strategy to decrease the NCD occurrence in Nelore calves.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherBioMed Centrales_AR
dc.relationinfo:eu-repograntAgreement/INTA/2019-PD-E5-I102-001/2019-PD-E5-I102-001/AR./Desarrollo de vacunas y tecnologías para mejorar las estrategias profilácticas y terapéuticas de las enfermedades que afectan la producción animal y la salud públicaes_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.sourceBMC Veterinary Research 18 : 323 (Agosto 2022)es_AR
dc.subjectBovine Rotaviruseng
dc.subjectRotavirus bovinoes_AR
dc.subjectCoronavirinaeeng
dc.subjectCalveseng
dc.subjectTerneroes_AR
dc.subjectVaccinationeng
dc.subjectVacunaciónes_AR
dc.subjectDiarrhoeaeng
dc.subjectDiarreaes_AR
dc.subjectChemoprophylaxiseng
dc.subjectProfilaxis Químicaes_AR
dc.subject.otherBovine Coronaviruseng
dc.subject.otherCoronavirus Bovinoes_AR
dc.titleEfficacy of prepartum vaccination against neonatal calf diarrhea in Nelore dams as a prevention measurees_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.description.origenInstituto de Virologíaes_AR
dc.description.filFil: Pinheiro, Filipe Aguera. University of São Paulo. College of Veterinary Medicine and Animal Science. Department of Internal Medicine; Brasiles_AR
dc.description.filFil: Decaris, Nathália. University of São Paulo. College of Veterinary Medicine and Animal Science. Department of Internal Medicine; Brasiles_AR
dc.description.filFil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). INCUINTA. Instituto de Virologia e Innovaciones Tecnologicas; Argentinaes_AR
dc.description.filFil: Parreño, Gladys Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Brandão, Paulo Eduardo. University of São Paulo. College of Veterinary Medicine and Animal Science. Department of Preventive Veterinary Medicine and Animal Health of Internal Medicine; Brasiles_AR
dc.description.filFil: Ayres, Henderson. MSD Animal Health; Brasiles_AR
dc.description.filFil: Gomes, Viviani. University of São Paulo. College of Veterinary Medicine and Animal Science. Department of Internal Medicine; Brasiles_AR
dc.subtypecientifico


Ficheros en el ítem

Thumbnail

Este ítem aparece en la(s) siguiente(s) colección(ones)

common

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/openAccess
Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/openAccess