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A prime-boost combination of a three-protein cocktail and multiepitopic MVA as a vaccine against Babesia bigemina elicits neutralizing antibodies and a Th1 cellular immune response in mice
(Elsevier, 2022-09)In the intraerythrocytic protozoan parasites of the genus Babesia both innate and adaptive immune responses are necessary to confer protection against clinical disease. In particular, the adaptive immune response involves ... -
Babesiosis prevalence in malaria-endemic regions of Colombia
(Wolters Kluwer, 2018-07)Background & objectives: The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity ... -
Casos de anaplasmosis, babesiosis y tripanosomiasis bovina registradas en el INTA Rafaela (2012-2019)
(Facultad de Ciencias Veterinarias, Universidad Nacional del Nordeste, 2022-06)Anaplasmosis, babesiosis y tripanosomiasis de los bovinos son enfermedades de importancia económica provocadas por Anaplasma marginale, Babesia bovis y/o Babesia bigemina, y Trypanosoma vivax, respectivamente. En este ... -
Descripción de dos casos de babesiosis cerebral en terneros de hasta 15 días de edad
(Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, 2020-06)La babesiosis es una enfermedad causada por Babesia bovis y Babesia bigemina, integrante del complejo conocido como “Tristeza bovina” y relevante en el Noroeste argentino (NOA). La presentación clínica de esta enfermedad ... -
Development of highly sensitive one step-PCR tests for improved detection of B. bigemina and B. bovis
(Elsevier, 2021-08)Bovine babesiosis caused by Babesia bigemina and B. bovis is an economically relevant tick-borne disease distributed over tropical and subtropical world regions. Animals that recover from the clinical disease can remain ... -
Estudio de la diversidad genética en poblaciones de Babesia bigemina de diferentes regiones geográficas
(Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, 2013)La babesiosis bovina es una enfermedad enzoótica causada por protozoarios Apicomplexa del género Babesia. En Argentina, esta enfermedad es provocada por B. bovis y B. bigemina, ambas trasmitidas por la garrapata Rhipicephalus ... -
Highly sensitive nested PCR and rapid immunochromatographic detection of Babesia bovis and Babesia bigemina infection in a cattle herd with acute clinical and fatal cases in Argentina
(Wiley, 2020-07)Bovine babesiosis is a tick‐transmitted haemoparasitic disease caused by Babesia bovis and B. bigemina affecting cattle of tropical and subtropical regions around the world. Pathogens are transmitted by the tick vector ... -
Identification and characterization of a Babesia bigemina thrombospondin-related superfamily member, TRAP-1 : a novel antigen containing neutralizing epitopes involved in merozoite invasion
(BioMed Central, 2020-12)Background: Thrombospondin-related anonymous protein (TRAP) has been described as a potential vaccine candidate for several diseases caused by apicomplexan parasites. However, this protein and members of this family have ... -
International interlaboratory validation of a nested PCR for molecular detection of Babesia bovis and Babesia bigemina, causative agents of bovine babesiosis
(Elsevier, 2022-04)Babesia bovis and B. bigemina are tick-transmitted parasites causing bovine babesiosis, characterized by significant morbidity and mortality leading to economic losses to the livestock industry in tropical and subtropical ... -
Typification of virulent and low virulence Babesia bigemina clones by 18S rRNA and rap-1c
(2014-06)The population structure of original Babesia bigemina isolates and reference strains with a defined phenotypic profile was assessed using 18S rRNA and rap-1c genes. Two reference strains, BbiS2P-c (virulent) and BbiS1A-c ...