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A safe and effective vaccine against bovine leukemia virus
Suarez Archilla, Guillermo; Gutierrez, Gerónimo; Camussone, Cecilia; Calvinho, Luis Fernando; Abdala, Alejandro Ariel; Alvarez, Irene; Petersen, Marcos; Franco, Lautaro Nahuel; De Stefano, Gabriel Alejandro; Monti, Gustavo; Jacques, Jean-Rock; Joris, Thomas; Willems, Luc; Trono, Karina Gabriela (Frontiers Media, 2022-08)Previous attempts to develop a vaccine against bovine leukemia virus (BLV) have not been successful because of inadequate or short-lived stimulation of all immunity components. In this study, we designed an approach based ... -
BLV: lessons on vaccine development
Abdala, Alejandro Ariel; Alvarez, Irene; Brossel, Hélène; Calvinho, Luis Fernando; Carignano, Hugo; Franco, Lautaro Nahuel; Gazon, Hélène; Gillissen, Christelle; Hamaidia, Malik; Hoyos, Clotilde; Jacques, Jean-Rock; Joris, Thomas; Laval, Florent; Petersen, Marcos Iván; Porquet, Florent; Porta, Natalia Gabriela; Ruiz, Vanesa; Safari, Rogaiyeh; Suarez Archilla, Guillermo Alejandro; Trono, Karina Gabriela; Willems, Luc (BMC, 2019-10-07)Vaccination against retroviruses is a challenge because of their ability to stably integrate into the host genome, undergo long-term latency in a proportion of infected cells and thereby escape immune response. Since ... -
Recent advances in BLV research
Barez, Pierre-Yves; De Brogniez, Alix; Carpentier, Alexandre; Gazon, Hélène; Gillet, Nicolas; Gutierrez, Gerónimo; Hamaidia, Malik; Jacques, Jean-Rock; Perike, Srikanth; Sriramareddy, Sathya Neelature; Renotte, Nathalie; Staumont, Bernard; Reichert, Michal; Trono, Karina Gabriela; Willems, Luc (MDPI, 2015-11)Different animal models have been proposed to investigate the mechanisms of Human T-lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull (NOG) mice, rabbits, squirrel monkeys, baboons and ...