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Early to late VSV-G expression in AcMNPV BV enhances transduction in mammalian cells but does not affect virion yield in insect cells

Simonin, Jorge Alejandro; Cuccovia Warlet, Franco Uriel; Bauzá, María del Rosario; Plastine, María Del Pilar; Alfonso, Victoria; Olea, Fernanda Daniela; Cerrudo, Carolina Susana; Belaich, Mariano Nicolás (MDPI, 2025-07)

Background/Objectives: Baculoviruses represent promising gene delivery vectors for mammalian systems, combining high safety profiles with substantial cargo capacity. While pseudotyping with vesicular stomatitis virus ...
P26 enhances baculovirus gene delivery by modulating the mammalian antiviral response

Amalfi, Sabrina; Plastine, María Del Pilar; Lopez, Maria Gabriela; Gravisaco, María José; Taboga, Oscar Alberto; Alfonso, Victoria (Springer, 2023-08)

Poxins are poxviral proteins that act by degrading 2´3´-cGAMP, a key molecule of cGAS-STING axis that drives and amplifies the antiviral response. Previous works have described some poxin homologous among lepidopteran and ...