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    • A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Carrillo, Elisa Cristina; Konig, Guido Alberto; Gismondi, Maria Ines (Oxford Academic Press, 2020-09)
      Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ...
    • Antiviral efficacy of short-hairpin RNAs and artificial microRNAs targeting foot and-mouth disease virus 

      Curra, Anabella Paola; Cacciabue, Marco Polo Domingo; Gravisaco, María José; Asurmendi, Sebastian; Taboga, Oscar Alberto; Gismondi, Maria Ines (Peer J Inc., 2021-06)
      RNA interference (RNAi) is a well-conserved mechanism in eukaryotic cells that directs post-transcriptional gene silencing through small RNA molecules. RNAi has been proposed as an alternative approach for rapid and specific ...
    • Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection 

      Gismondi, Maria Ines; Ortiz, Xoana P.; Curra, Anabella Paola; Asurmendi, Sebastian; Taboga, Oscar Alberto (2014-04)
      RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...
    • Differential replication of Foot-and-mouth disease viruses in mice determine lethality 

      Cacciabue, Marco Polo; Garcia Nuñez, Maria Soledad; Delgado, Fernando Oscar; Curra, Anabella Paola; Marrero Diaz De Villegas, Rubén; Molinari, Maria Paula; Rieder, Elizabeth; Carrillo, Elisa Cristina; Gismondi, Maria Ines (2017-09)
      Adult C57BL/6J mice have been used to study Foot-and-mouth disease virus (FMDV) biology. In this work, two variants of an FMDV A/Arg/01 strain exhibiting differential pathogenicity in adult mice were identified and ...
    • In vitro developmental competence of bovine demi-embryos generated by blastomere separation and blastocyst bisection 

      Ynsaurralde Rivolta, Amanda Eugenia; Gambini, Andrés; Alberio, Virgilia; Savy, Virginia; Ratner, Laura Daniela; Guberman, Alejandra; Vazquez Echegaray, Camila; Gismondi, Maria Ines; Curra, Anabella Paola; Bevacqua, Romina Jimena; Salamone, Daniel Felipe (Wiley, 2024-06)
      The efficiency of bovine in vitro embryo production can be significantly improved by splitting embryos at different stages. However, the blastocyst quality of in vitro-produced demi-embryos remains unexplored. The objective ...
    • ViralPlaque: a Fiji macro for automated assessment of viral plaque statistics 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Gismondi, Maria Ines (PeerJ, 2019-09)
      laque assay has been used for a long time to determine infectious titers and characterize prokaryotic and eukaryotic viruses forming plaques. Indeed, plaque morphology and dimensions can provide information regarding the ...