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The localization of a heterologous displayed antigen in the baculovirus-budded virion determines the type and strength of induced adaptive immune response

Tavarone, Maria Eugenia; Molina, Guido Nicolas; Amalfi, Sabrina; Peralta, Andrea Veronica; Molinari, Maria Paula; Taboga, Oscar Alberto; Diaz, Silvio Ricardo; Gravisaco, María José (2017-05)

In the search of strategies of presentation of heterologous antigens to elicit humoral or cellular immune responses that modulate and properly potentiate each type of response, researchers have been studying baculovirus ...
Two distinctive phenotypes of AcMNPV display different immune abilities and intracellular destiny

Molina, Guido Nicolas; Tavarone, Maria Eugenia; Taboga, Oscar Alberto; Molinari, Maria Paula (2016-12-29)

The budded phenotype (BV) of the baculovirus AcMNPV has been demonstrated to have strong immunostimulatory properties that are relevant for the development of vaccines and antiviral therapies. Although the occluded ...