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Efficacy of a recombinant Intimin, EspB and Shiga toxin 2B vaccine in calves experimentally challenged with Escherichia coli O157:H7
Martorelli, Luisina; Garimano, Nicolás; Fiorentino, Gabriela A.; Vilte, Daniel Alejandro; Garbaccio, Sergio Gabriel; Barth, Stefanie A.; Menge, Christian; Ibarra, Cristina Adriana; Palermo, Marina Sandra; Cataldi, Angel Adrian (Elsevier, 2018-06)Escherichia coli O157:H7 is a zoonotic pathogen of global importance and the serotype of Shiga toxin-producing E. coli (STEC) most frequently associated with Hemolytic Uremic Syndrome (HUS) in humans. The main STEC reservoir ... -
Immune response in calves vaccinated with type three secretion system antigens and shiga toxin 2B subunit of Escherichia coli O157:H7
Martorelli, Luisina; Garbaccio, Sergio Gabriel; Vilte, Daniel Alejandro; Albanese, Adriana Andrea; Mejías, María Pilar; Palermo, Marina Sandra; Mercado, Elsa Cristina; Ibarra, Cristina E.; Cataldi, Angel Adrian (2017-01-03)Ruminants are the primary reservoir of Shiga-toxin producing Escherichia coli (STEC) O157:H7 and the main source of infection for humans. The aim of this study was to assess the immunogenic properties of a candidate vaccine ... -
Shiga toxin-producing Escherichia coli (STEC) O22:H8 isolated from cattle reduces E. coli O157:H7 adherence in vitro and in vivo
Martorelli, Luisina; Albanese, Adriana Andrea; Vilte, Daniel Alejandro; Cantet, Rodolfo Juan Carlos; Bentancor, Adriana Beatriz; Zolezzi, Gisela; Chinen, Isabel; Ibarra, Cristina E.; Rivas, Marta; Mercado, Elsa Cristina; Cataldi, Angel Adrian (2017-09)Problem addressed: Shiga toxin-producing Escherichia coli (STEC) are a group of bacteria responsible for foodassociated diseases. Clinical features include a wide range of symptoms such as diarrhea, hemorrhagic colitis and ...