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A spatiotemporal analysis of bovine brucellosis cases in dairy herds from Argentina, from 2014 to 2023
Novoa, María Belén; Aguirre, Nerina; Ugarte, Estefanía; Foster, Camila Nayla; Molineri, Ana Ines; Signorini Porchiett, Marcelo Lisandro; Molina, Alberto Martín; Vanzini, Victor Rene (Springer, 2025-09)Brucellosis is a bacterial infection that causes abortion in cattle, poses a significant public health risk, and causes economic losses in livestock production. This study analyzed passive epidemiological surveillance data ... -
Abortion associated with Brucella abortus strain RB51 vaccination during gestation in a dairy cow immunized with strain 19 as a calf
Cabaña, Enzo; Rejf, Paula; Zbrun, Maria Virginia; Marini, Maria del Rocio; Ilardo, Andres; Machado, Selva; Garnero, Oscar; Foster, Camila Nayla; Novoa, María Belén (Elsevier, 2025-12)Bovine brucellosis, caused by Brucella abortus, is a zoonotic disease that leads to abortions in cattle and poses a public health risk. Vaccination with live attenuated strains, including S19 and RB51, is part of control ... -
Brucelosis Caprina en la Argentina Vol. II. Período 2014-2022
Robles, Carlos Alejandro; Spath, Ernesto Juan; Vanzini, Victor Rene; Carosio, Agustin; Novoa, María Belén; Aguirre, Daniel Hector; Alberghini, Juan Pablo; Smeriglio, Aldo Rafael; Martinez, Agustin (EEA Balcarce, INTA, 2025-07)La brucelosis caprina es una enfermedad infecto-contagiosa de distribución mundial, de curso crónico, causada por alguno de los tres biovares (bv) de Brucella melitensis (B. melitensis), con un alto impacto en la producción ... -
Casos de anaplasmosis, babesiosis y tripanosomiasis bovina registradas en el INTA Rafaela (2012-2019)
Mazzucco Panizza, Matilde Nahimé; Novoa, María Belén; Sarli, Macarena; Signorini Porchiett, Marcelo Lisandro; Echaide, Ignacio Eduardo (Facultad de Ciencias Veterinarias, Universidad Nacional del Nordeste, 2022-06)Anaplasmosis, babesiosis y tripanosomiasis de los bovinos son enfermedades de importancia económica provocadas por Anaplasma marginale, Babesia bovis y/o Babesia bigemina, y Trypanosoma vivax, respectivamente. En este ... -
Development and Bayesian analysis of a competitive inhibition ELISA for caprine brucellosis
Foster, Camila Nayla; Monzon, Nolly María; Signorini Porchiett, Marcelo Lisandro; Aznar, Maria Natalia; Aguirre, Nerina Patricia; Valentini, Beatriz Susana; Vanzini, Víctor René; Novoa, María Belén (Elsevier, 2025-05)Caprine brucellosis, caused by Brucella melitensis, is a zoonotic disease responsible for abortions in goats and is endemic in several countries. Control measures include vaccination, serological assays, and culling of ... -
Development and Bayesian validation of a competitive inhibition ELISA for detection of antibodies against Brucella abortus in cattle
Novoa, María Belén; Aguirre, Nerina; Valentini, Beatriz Susana; Signorini Porchiett, Marcelo Lisandro; Aznar, Maria Natalia; Vanzini, Victor Rene; Torioni, Susana Marta (Elsevier, 2024-09)Bovine brucellosis is a zoonotic disease caused by Brucella abortus, responsible for abortions in cows. It is endemic in low- and middle-income countries, where the brucellosis control and eradication programs are based ... -
Development and evaluation of a double-antigen sandwich ELISA to identify Anaplasma marginale–infected and A. centrale–vaccinated cattle
Sarli, Macarena; Thompson, Carolina Soledad; Novoa, María Belen; Valentini, Beatriz Susana; Mastropaolo, Mariano; Echaide, Ignacio Eduardo; Torioni, Susana Marta; Primo, María Evangelina (American Association of Veterinary Laboratory Diagnosticians, 2019-11)Bovine anaplasmosis is a worldwide infectious disease caused by the intraerythrocytic bacterium Anaplasma marginale, which is transmitted by ticks and fomites. A. centrale is a less virulent subspecies used as a live ... -
Development of a novel fusion protein with Anaplasma marginale and A. centrale MSP5 improved performance of Anaplasma antibody detection by cELISA in infected and vaccinated cattle
Primo, María Evangelina; Thompson, Carolina Soledad; Valentini, Beatriz Susana; Sarli, Macarena; Novoa, María Belen; Mangold, Atilio Jose; Torioni, Susana Marta (Plos One, 2019-01-23)Detection of antibodies to Anaplasma spp. using commercial competitive enzyme-linked immunosorbent assay (ccELISA) is based on the recombinant major surface protein 5 fused to maltose binding protein (MBP-MSP5) or glutathione ... -
Development, validation and field evaluation of an indirect ELISA for the detection of antibodies against Brucella abortus in bulk and individual milk samples in dairy cattle
Novoa, María Belén; Aguirre, Nerina; Valentini, Beatriz Susana; Torioni, Susana Marta; Signorini Porchiett, Marcelo Lisandro; Primo, María Evangelina; Elena, Sebastián Alejandro; Vanzini, Victor Rene (Elsevier, 2022-11)Brucellosis is an abortigenic and zoonotic disease. In cattle, it is mainly caused by Brucella abortus. The disease is endemic in low- and middle-income countries, being considered a neglected zoonotic disease. In these ... -
Diagnóstico y prevención de la neosporosis bovina. Desarrollo de técnicas serológicas y evaluación de inmunógenos basados en proteínas recombinantes
Novoa, María Belén (Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, 2019)La neosporosis es una enfermedad abortígena, causada por el parásito protozoario Neospora caninum. No hay tratamientos o vacunas disponibles, el control se basa en el diagnóstico y las estrategias de manejo. Se desarrollaron ... -
Evaluation of a competitive inhibition ELISA based on the recombinant protein tSAG1 to detect anti–Neospora caninum antibodies in cattle
Novoa, María Belén; Valentini, Beatriz Susana; Torioni, Susana Marta; Primo, María Evangelina; Echaide, Ignacio Eduardo (American Association of Veterinary Laboratory Diagnosticians (AAVLD), 2020-05)Neospora caninum is a protozoan parasite that causes abortion and important economic losses in cattle worldwide. There are no treatments or vaccines available; disease control is based on diagnosis and herd management ... -
Evaluation of frequency of antibodies against Neospora caninum, Toxoplasma gondii and Brucella melitensis, risk factors and spatial distribution of infection in goat and sheep flocks from Argentina
Novoa, María Belén; Aguirre, Nerina; Ormaechea, Nadia; Palmero, Sebastian; Valentini, Beatriz Susana; Vanzini, Victor Rene; Molineri, Ana Ines (Elsevier, 2023-11)Neospora caninum, Toxoplasma gondii and Brucella melitensis are pathogens that cause abortion in small ruminants. Besides, B. melitensis and T. gondii are zoonotic pathogens. The aim of this study was to describe the ... -
Neospora caninum truncated recombinant proteins formulated with liposomes and CpG-ODNs triggered a humoral immune response in cattle after immunisation and challenge
Novoa, María Belén; Sarli, Macarena; Reidel, Ivana Gabriela; Veaute, Carolina Melania Isabel; Valentini, Beatriz Susana; Primo, María Evangelina (Elsevier, 2021-06)Abortions caused by Neospora caninum are a serious problem in cattle production and require effective immunoprophylaxis. The objective of this work was to assess the humoral immune response to four recombinant (r) N. caninum ... -
Preliminary Study on Artificial versus Animal-Based Feeding Systems for Amblyomma Ticks (Acari: Ixodidae)
Sebastian, Patrick; Król, Nina; Novoa, María Belén; Nijhof, Ard Menzo; Pfeffer, Martin; Nava, Santiago; Obiegala, Anna (MDPI, 2023-05)Hard ticks pose a threat to animal and human health. Active life stages need to feed on a vertebrate host in order to complete their life cycle. To study processes such as tick-pathogen interactions or drug efficacy and ... -
Use and comparison of serologic assays to detect anti-Neospora caninum antibodies in farmed red deer (Cervus elaphus)
Novoa, María Belén; Soler, Juan Pablo; Cirone, Karina Mariela; Hecker, Yanina; Valentini, Beatriz Susana; Primo, María Evangelina; Moore, Prando Dadin (Elsevier, 2023-01)Neospora caninum is a protozoan parasite that cause abortion in different ruminant species, including red deer ( Cervus elaphus). There are no validated assays to be performed with sera from red deer. At the present work, ... -
A vaccine using Anaplasma marginale subdominant type IV secretion system recombinant proteins was not protective against a virulent challenge
Sarli, Macarena; Novoa, María Belen; Mazzucco Panizza, Matilde Nahimé; Signorini, Marcelo; Echaide, Ignacio Eduardo; Echaide, Susana T. de; Primo, María Evangelina (PLOS; National Center for Biotechnology Information, 2020-02)Anaplasma marginale is the most prevalent tick-borne livestock pathogen with worldwide distribution. Bovine anaplasmosis is a significant threat to cattle industry. Anaplasmosis outbreaks in endemic areas are prevented via ... -
Validation and field evaluation of a competitive inhibition ELISA based on the recombinant protein tSAG1 to detect anti-Neospora caninum antibodies in sheep and goats
Novoa, María Belen; Aguirre, Nerina; Ormaechea, Nadia; Palmero, Sebastián; Rouzic, Lisandro; Valentini, Beatriz Susana; Sarli, Macarena; Orcellet, Viviana Mercedes; Marengo, Rafael; Vanzini, Victor Rene; Primo, María Evangelina (Elsevier, 2020-08)Neospora caninum is a protozoan parasite that causes abortion and reproductive failure in small ruminants. We validated and evaluated under field conditions a competitive inhibition ELISA based on the truncated SAG1 protein ...