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Assessment of tuberculosis biomarkers in paratuberculosis-infected cattle
Klepp, Laura Ines; Colombatti Olivieri, Maria Alejandra; Moyano, Roberto Damian; Romano, Maria Isabel; Malovrh, Tadej; Ocepek, Matjaž; Blanco, Federico Carlos; Bigi, Fabiana (Sciendo, 2023-03)Introduction: Mycobacterium bovis and Mycobacterium avium subsp. paratuberculosis, respectively the causative agents of bovine tuberculosis (bTB) and bovine paratuberculosis (PTB), share a high number of antigenic proteins. ... -
Development of a lateral flow immunochromatography test for the rapid detection of bovine tuberculosis
Alonso, Maria Natalia; Griffa, Natanael; Moyano, Roberto Damián; Mon, Maria Laura; Colombatti Olivieri, Maria Alejandra; Barandiaran, Soledad; Martinez Vivot, Marcela; Fiorini, Gonzalo; Canal, Ana María; Santangelo, María De La Paz; Singh, Mahavir G.; Romano, Maria Isabel (Elsevier, 2021-04)Detection of specific antibodies would be a useful test strategy for bovine tuberculosis (bTB) as a complement to the single skin test. We developed a lateral flow immunochromatography (LFIC) test for rapid bTB detection ... -
Editorial : Vaccination strategies against ruminant infectious diseases
Del Medico Zajac, Maria Paula; Moyano, Roberto Damian; Colombatti Olivieri, Maria Alejandra (Frontiers Media, 2023-05)Ruminant infectious diseases cause economic impact through losses in animal production and human health. Most of the commercially available veterinary vaccines are live attenuated or inactivated which induce different ... -
Evaluation of a virulent strain of Mycobacterium avium subsp. Paratuberculosis used as a heat-killed vaccine
Colombatti Olivieri, Maria Alejandra; Moyano, Roberto Damian; Mon, Maria Laura; Gravisaco, María José; Alvarado Pinedo, María Fiorella; Delgado, Fernando Oscar; Hernández Pando, Rogelio; Alonso, Maria Natalia; Cuerda, Maria Ximena; Santangelo, María De La Paz; Romano, Maria Isabel (Elsevier, 2021-11)Bovine paratuberculosis is one of the most important chronic infectious diseases in livestock. This disease is difficult to control because of its inefficient management (test and cull strategy and inadequate biosecurity). ... -
Genomic comparison of two strains of Mycobacterium avium subsp. paratuberculosis with contrasting pathogenic phenotype
Colombatti Olivieri, Maria Alejandra; Fresia, Pablo; Graña, Martín; Cuerda, Maria Ximena; Nagel, Ariel Gaston; Alvarado Pinedo, Maria Fiorella; Romano, Maria Isabel; Caimi, Karina Cynthia; Berná, Luisa; Santangelo, María De La Paz (Elsevier, 2023-01)In a previous study, we evaluated the degree of virulence of Mycobacterium avium subsp. paratuberculosis (Map) strains isolated from cattle in Argentina in a murine model. This assay allowed us to differentiate between ... -
Pathogenesis of domestic pigs submitted to mycobacterial sensitizations previous to experimental infection with Mycobacterium bovis
Cuerda, Maria Ximena; Colombatti Olivieri, Maria Alejandra; Gravisaco, María José; Marfil, Maria Jimena; Barandiaran, Soledad; Sevilla, Iker A.; Garrido, Joseba M.; Moyano, Roberto Damian; Zumarraga, Martin Jose; Romano, Maria Isabel; Juste, Ramón A.; Santangelo, María De La Paz (INIA (España), 2022-03)Aim of study: To demonstrate the virulence of a Mycobacterium bovis local pig isolate in order to contribute to a better understanding of the pathological and immunological consequences of M. bovis infection in previous ... -
Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model
Colombatti Olivieri, Maria Alejandra; Moyano, Roberto Damian; Traveria, Gabriel Eduardo; Alvarado Pinedo, Maria Fiorella; Mon, Maria Laura; Gravisaco, María José; Delgado, Fernando Oscar; Santangelo, María De La Paz; Romano, Maria Isabel (Elsevier, 2018-12)Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include ... -
Transmissibility of Mycobacterium pinnipedii in a murine model
Marfil, Maria Jimena; Blanco, Federico Carlos; Colombatti Olivieri, Maria Alejandra; Eirin, Maria Emilia; Zumarraga, Martin Jose (Frontiers Media, 2024-03)The causative agent of tuberculosis in pinnipeds is Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis complex (MTC). The natural hosts are pinnipeds; however, other non-marine mammals, including humans, ...