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Assessment on different vaccine formulation parameters in the protection against heterologous challenge with FMDV in cattle
Di Giacomo, Sebastián; Bucafusco, Danilo; Schammas, Juan Manuel; Pega, Juan Franco; Miraglia, Maria Cruz; Barrionuevo, Florencia Mabel; Capozzo, Alejandra; Perez Filgueira, Daniel Mariano (MDPI, 2022-08)Foot-and-mouth disease (FMD) remains one of the major threats to animal health worldwide. Its causative agent, the FMD virus (FMDV), affects cloven-hoofed animals, including farm animals and wildlife species, inflicting ... -
Kinetics of foot-and-mouth disease vaccine-induced antibody responses in buffaloes (Bubalus bubalis): avidity ELISA as an alternative to the virus neutralization test
Sala, Juan Manuel; Mansilla, Florencia Celeste; Miraglia, Maria Cruz; Caspe, Sergio Gaston; Perez Filgueira, Daniel Mariano; Capozzo, Alejandra (Frontiers Media, 2023-11)The role of water buffaloes in foot-and-mouth disease (FMD) epidemiology as one of the major hosts of the virus that can develop persistent asymptomatic infection highlights the importance of sustaining surveillance on the ... -
The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine
Mansilla, Florencia Celeste; Turco, Cecilia Soledad; Miraglia, Maria Cruz; Bessone, Fernando Aníbal; Franco, Raul Enrique; Perez Filgueira, Daniel Mariano; Sala, Juan Manuel; Capozzo, Alejandra (Plos One, 2020-05)The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against ...