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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
Richetta, Matias Daniel; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Gravisaco, María José; Calamante, Gabriela; Berinstein, Analia (2017-01)Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ... -
Development of diagnostic tools for IBDV detection using plants as bioreactors
Gomez, Evangelina Raquel; Cassani, María Florencia; Lucero, Maria Soledad; Parreño, Viviana; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (SpringerOpen, 2020-05)Infectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric ... -
Developments in plant-based vaccines against diseases of concern in developing countries
Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Carrillo, Elisa Cristina; Berinstein, Analia (BENTHAM Open, 2010)Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where ... -
Evasion of maternal antibody protection by an IBDV Argentine variant
Jaton, Juan Marcelo; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Rizzi, Lucia; Gravisaco, María José; Pinto, Silvina; Berinstein, Analia; Chimeno Zoth, Silvina Andrea (Elsevier, 2024-03)Infectious bursal disease (IBD) is a viral disease that affects the ability of chickens to produce humoral immune responses. One way to prevent the disease is the passage of maternally derived antibodies (MDA) from dams ... -
Immunomodulatory effect of baculovirus in chickens : how it modifies the immune response against infectious bursal disease virus
Chimeno Zoth, Silvina Andrea; Carballeda, Juan Manuel; Gravisaco, María José; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Berinstein, Analia (2016)Several reports have shown that baculoviruses (BVs) have strong adjuvant properties on the mammalian immune system. Recent studies of our group demonstrated the ability of BV to stimulate the innate immunity in chickens. ... -
Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein
Carballeda, Juan Manuel; Maroniche, Guillermo Andrés; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (Elsevier, 2015-09)Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ... -
Plant-based vaccine candidate against Infectious bursal disease: an alternative to inactivated vaccines for breeder hens
Lucero, Maria Soledad; Richetta, Matias Daniel; Chimeno Zoth, Silvina Andrea; Jaton, Juan; Pinto, Silvina; Canet, Zulma Edith; Berinstein, Analia; Gomez, Evangelina Raquel (Elsevier, 2019-08)Infectious bursal disease (IBD) is an acute, highly contagious immunosuppressive disease that affects young birds causing important economic losses in the poultry industry worldwide. Strict hygiene management together with ... -
Research Note : Characterization and phylodynamic analysis of new infectious bursal disease virus variants circulating in Argentina
Jaton, Juan Marcelo; Lozano Calderon, Laura Camila; Gambini, Pablo; Ponti, Marina; Gomez, Evangelina Raquel; Konig, Guido Alberto; Chimeno Zoth, Silvina Andrea (Elsevier, 2024-06)Infectious Bursal Disease is a highly contagious disease that affects young chickens and leads to significant economic losses. Its causal agent is a double-stranded RNA virus that, due to its high error rate during the ... -
Study of coinfection with local strains of infectious bursal disease virus and infectious bronchitis virus in specific pathogen-free chickens
Jaton, Juan Marcelo; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Gravisaco, María José; Pinto, Silvina; Vagnozzi, Ariel Eduardo; Craig, María Isabel; Di Giacomo, Sebastián; Berinstein, Analia; Chimeno Zoth, Silvina Andrea (Elsevier, 2023-12)Immunosuppressive diseases cause great losses in the poultry industry, increasing the susceptibility to infections by other pathogens and promoting a suboptimal response to vaccination. Among them, infectious bursal disease ... -
Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against Infectious Bursal Disease Virus
Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Carballeda, Juan Manuel; Gravisaco, María José; Berinstein, Analia (Elsevier, 2013-05-28)Infectious Bursal Disease Virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds. This disease causes important economic losses in the poultry industry worldwide. ...