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A direct high-throughput in Cell-ELISA for measuring infectivity of cytopathic and non-cytopathic bovine viral diarrhoea virus strains applied to the assessment of antiviral activity
Quintana, Maria Eugenia; Barone, Lucas; Forlenza, María Belén; Trotta, Myrian Vanesa; Turco, Cecilia; Mansilla, Florencia Celeste; Cardoso, Nancy Patricia; Capozzo, Alejandra Victoria (Elsevier, 2018-07-19)Low-cost high-throughput methods applicable to any virus strain are required for screening antiviral compounds against multiple field strains. Colorimetric cell-viability assays are used for this purpose as long as the ... -
Alternatives for the serological assessment of foot-and-mouth disease vaccine immunity in buffaloes (Bubalus bubalis)
Sala, Juan Manuel; Trotta, Myrian Vanesa; Mansilla, Florencia Celeste; Perez Filgueira, Daniel Mariano; Caspe, Sergio Gaston; Capozzo, Alejandra (2018)Buffaloes are compulsory vaccinated against foot-and-mouth disease virus (FMDV) in many countries as part of the official control programmes. Serological testing aimed to indirectly assess herd immunity is currently performed ... -
Desarrollo y evaluación de tecnología para la detección de proteínas no estructurales del Virus de la Fiebre Aftosa en formulaciones vacunales
Trotta, Myrian Vanesa (Universidad Nacional de San Martín, 2009)La fiebre aftosa (FA) es una enfermedad viral altamente contagiosa que afecta a todas las especies de pezuña hendida, salvajes y domésticas. Las especies domésticas principalmente afectadas son los bovinos, porcinos, ovinos ... -
In-vivo activity of IFN-λ and IFN-α against bovine-viral-diarrhea virus in a mouse model
Quintana, Maria Eugenia; Barone, Lucas Jose; Trotta, Myrian Vanesa; Turco, Cecilia Soledad; Mansilla, Florencia Celeste; Capozzo, Alejandra; Cardoso, Nancy (Frontiers Media, 2020-02)Bovine-viral-diarrhea virus (BVDV) can cause significant economic losses in livestock. The disease is controlled with vaccination and bovines are susceptible until vaccine immunity develops and may remain vulnerable if a ... -
Recombinant occlusion bodies of baculovirus as carriers of a nonstructural protein of foot-and-mouth disease virus
Diez, Michay; Trotta, Myrian Vanesa; Alfonso, Victoria; Taboga, Oscar Alberto; Lopez, Maria Gabriela (Springer, 2018-11)Here, we developed a diagnostic ELISA for foot-and-mouth disease using recombinant occlusion bodies (rOBs) of baculovirus. We fused Δ3AB1–3, a polypeptide derived from non-structural proteins of foot-and-mouth disease ...