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Aborto por Leptospira en una yegua en Salta, Argentina
Micheloud, Juan Francisco; Martinez, Mara Leila; Zurita, Sofía G.; Grune Loffler, Sylvia; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (2015)La leptospirosis en equinos es generalmente asintomática, aunque existen regiones donde la enfermedad constituye un problema. Aquí se describe un caso de aborto en yegua debido a la infección por este agente. Se efectuó ... -
Aislamiento de una cepa patógena de Leptospira spp del medio ambiente
Brihuega, Bibiana Felicitas; Hamer, Micaela; Esteban, Micaela; Saraullo, Vanina Rosa; Sanchez, Maria Cristina; Grune Loffler, Sylvia; Vilte, Daniel Alejandro; Martinez, Mara Leila (Universidad de Buenos Aires, 2025-10)La producción animal enfrenta nuevos desafíos relacionados con los riesgos potenciales de contaminación microbiológica del ambiente. La proximidad y concentración de animales favorece la transmisión de patógenos, y la ... -
Appication of loop-mediated isothermal amplification as a tool for environmental surveillance of leptospiral reservoirs
Hamer, Micaela; Saraullo, Vanina Rosa; Muschetto, Emiliano; Esteban, Micaela; Tripodi, Mariel Alejandra; Sanchez, Maria Cristina; Hancke, Diego; Suárez, Olga Virginia; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Sociedad Argentina de Microbiología General, 2025-08)Leptospirosis is a globally important zoonosis caused by pathogenic strains of the genus Leptospira, affecting domestic and wild animals as well as humans. The survival of leptospires in the environment plays a key role ... -
Comparison of ELISA using recombinant LipL32 and sonicated antigen of leptospira for detecting bovine leptospirosis
Martinez, Mara Leila; Rodriguez, Marcelo A.; Saraullo, Vanina Rosa; Irazu, Lucía E.; Hamer, Micaela; Watanabe, Olivia; Grune Loffler, Sylvia; Romero, Graciela Noemi; Samartino, Luis Ernesto; Brihuega, Bibiana Felicitas (Elsevier, 2022-01)Leptospirosis is one of the most widely distributed zoonosis in the world. Bovine leptospirosis is a serious problem in bovine production, causing reproductive losses. The aim of this work was to compare recombinant LipL32 ... -
Detección de Leptospira spp. (Spirochaetales: Leptospiraceae) en muestras ambientales de regiones habitadas por poblaciones vulnerables del norte argentino
Grune Loffler, Sylvia; Periago, María Victoria; Watanabe, Olivia; Saraullo, Vanina Rosa; Aldama, Evangelina; Cejas, Graciela; Cruz, Diego; Delgado, Cintia; Goizueta, Carolina; Hamer, Micaela; Martinez, Mara Leila; Brihuega, Bibiana Felicitas (Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, 2021-12)La leptospirosis continúa siendo hoy en día un problema para la salud pública, principalmente en poblaciones de bajos recursos socioeconómicos. En este trabajo se presenta la detección de leptospiras patógenas en muestras ... -
Detection of leptospiral antibodies in wild animals in aquatic environments of Argentina
Brihuega, Bibiana Felicitas; Saraullo, Vanina Rosa; Hamer, Micaela; Esteban, Micaela; Sanchez, Maria Cristina; Samartino, Luis Ernesto; Martinez, Mara Leila (International Leptospirosis Society, 2024-09)Zoonoses are defined as diseases of animals that are transmitted naturally to hu mans, directly or indirectly. Indirect transmission can manifest itself through the pres ence of these pathogens in the environment. The ... -
Diferenciación de serovares de leptospiras patógenas mediante PCR del gen ligB y secuenciación = Differentiation of pathogenic leptospires spp by PCR of ligB gene and sequencing
Martinez, Mara Leila; Grune Loffler, Sylvia; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (Asociación Argentina de Microbiología, 2018)La leptospirosis es la zoonosis de mayor distribución mundial. El objetivo del presente trabajo fue desarrollar una técnica molecular que diferencie leptospiras patógenas. Se amplificó mediante PCR y se secuenció una ... -
Discriminación genotípica de serovariedades del serogrupo Icterohaemorrhagiae pertenecientes a Leptospira interrogans (Spirochaetales: Leptospiraceae) y el análisis de distancias génicas mediante coordenadas principales
Grune Loffler, Sylvia; Martinez, Mara Leila; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (2017-01-18)La leptospirosis es una zoonosis de amplia distribución mundial y de importancia en salud pública y veterinaria. El serogrupo Icterohaemorrhagiae toma importancia, ya que ha sido aislado con frecuencia en roedores y en ... -
Discriminación genotípica de serovariedades del serogrupo Icterohaemorrhagiae pertenecientes a Leptospira interrogans (Spirochaetales: Leptospiraceae) y el análisis de distancias génicas mediante coordenadas principales = Genotypic discrimination of serovars belonging to the serogroup Icterohaemorrhagiae of Leptospira interrogans (Spirochaetales: Leptospiraceae) and the analysis of genetic distances using principal coordinates
Grune Loffler, Sylvia; Martinez, Mara Leila; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias, 2016)La leptospirosis es una zoonosis de amplia distribución mundial y de importancia en salud pública y veterinaria. El serogrupo Icterohaemorrhagiae toma importancia, ya que ha sido aislado con frecuencia en roedores y en ... -
Enhanced detection of Leptospira in cattle : Comparative performance of loop-mediated isothermal amplification, polymerase chain reaction and serological methods
Hamer, Micaela; Saraullo, Vanina Rosa; Esteban, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Elsevier, 2025-09)Leptospirosis is a globally distributed zoonotic disease. This study aimed to evaluate the performance of loop-mediated isothermal amplification (LAMP) in detecting Leptospira DNA in bovine samples compared to conventional ... -
Estudio de las posibles causas de mermas reproductivas luego del servicio en la cría bovina en el Noroeste Argentino = Study of the possible causes of post mating reproductive losses in beef cattle farming in Northwest Argentine = Estudo das possíveis causas de perdas reprodutivas após serviço na criação bovina no Noroeste Argentino
Suarez, Victor Humberto; Micheloud, Juan Francisco; Martinez, Gabriela Marcela; Colque Caro, Luis Adrián; Olmos, Leandro Hipolito; Martinez, Mara Leila; Louge Uriarte, Enrique L.; Verna, Andrea Elizabeth; Gos, María Laura (Facultad de Ciencias Veterinarias, Universidad Nacional de La Pampa, 2024-02-14)Con el propósito de diagnosticar la presencia de posibles causas de mermas reproductivas se realizaron encuestas y conformaron 4 grupos de vientres bovinos luego de finalizado el servicio en 5 establecimientos salteños de ... -
Evaluation of LigB polymerase chain reaction as a complementary tool to microscopic agglutination test for the detection of bovine leptospirosis in serum samples
Saraullo, Vanina Rosa; Hamer, Micaela; Esteban, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Elsevier, 2025-05)Leptospirosis is a significant infectious disease affecting livestock. Microscopic agglutination test (MAT) is used as the gold standard; however, the inclusion of molecular tools (PCR) could improve the accuracy of ... -
First isolation of Leptospira borgpetersenii from Fetuses of Wild boars (Sus scrofa)
Brihuega, Bibiana Felicitas; Grune Loffler, Sylvia; Samartino, Luis Ernesto; Romero, Graciela Noemi; Auteri, Carmelo Domingo; Martinez, Mara Leila (2017-02-07)Leptospirosis is a worldwide zoonose and is endemic in many countries. This zoonosis is maintained in nature by chronic renal infection of carrier animals, being rodents and other small mammals the most important reservoirs. ... -
First record of the presence of antibodies against Leptospira in Lagostomus maximus, and Leptospira weillii serogroup Celledoni in Chaetophractus villosus, Argentina
Kin, Marta Susana; Sanchez, Maria Cristina; Esteban, Micaela; Martinez, Mara Leila; Brihuega, Bibiana Felicitas; Hamer, Micaela; Saraullo, Vanina Rosa; Cayron, Eduardo D.; Cayron, Gabriel P.; Gimenez, Hugo Daniel; Cayron, Carlos R.; Fort, Marcelo Cristian (Elsevier, 2025-03)Leptospirosis is a zoonosis with a worldwide distribution, which is transmitted through direct contact with infected animals or by contact with contaminated water or soil. Objectives was to examine the presence of antibodies ... -
First report of pathogenic Leptospira spp. in Tadarida brasiliensis bats (family Molossidae) and Eptesicus furinalis (family Vespertilionidae) of Argentina. New host species in this country? = Primer reporte de Leptospira spp. patógena en murciélagos Tadarida brasiliensis (familia: Molossidae) y Eptesicus furinalis (familia: Vespertilionidae) en Argentina. ¿Nuevas especies hospedadoras en el país?
Saraullo, Vanina Rosa; Grune Loffler, Sylvia; Pastorino, Florencia; Watanabe, Olivia; Alonso, Maria Laura; Hamer, Micaela; Moreira, Cecilia; Martinez, Mara Leila; Martinez, Gustavo; Brihuega, Bibiana Felicitas (Elsevier, 2021-09)Leptospirosis is an endemic disease caused by Leptospira spp., a bacterium that affects animals and humans. In recent years, the number of reports of leptospirosis in wild animals has increased, which highlights the need ... -
Identificación morfológica y molecular de Cysticercus fasciolaris aislado de un roedor (Rattus norvegicus) de la provincia de Buenos Aires (Argentina) = Morphological and molecular identification of Cysticercus fasciolaris isolated from rodent hosts (Rattus norvegicus) in Buenos Aires province (Argentina)
Martinez, Mara Leila; Dominguez, Mariana Gabriela; Morici, Gabriel Edgardo; Cavia, Regino; Montes de Oca, Daniela P.; Lovera, Rosario; Schapiro, Javier Hernan; Caracostantogolo, Jorge Luis (Elsevier, 2013-07)En un estudio exploratorio de roedores de la especie Rattus norvegicus de la provincia de Buenos Aires, se observó que ciertos metacestodos de tenias se encontraban enquistados en el hígado del hospedador. Nuestro objetivo ... -
In silico evaluation of Lipl32 peptides for antigen candidates in leptospirosis diagnostic
Esteban, Micaela; Saraullo, Vanina Rosa; Madero, Agustin; Hamer, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (International Leptospirosis Society, 2024-09)Leptospirosis is a zoonotic infectious disease caused by the spirochete of the genus Leptospira. The gold-standard technique for diagnosis is the microscopic agglutina tion test, however, this serological test is complex ... -
New enzyme-linked immunoassay for the detection of specific antibodies against multiple Leptospira serogroups in bovine sera
Martinez, Mara Leila; Rodriguez, Marcelo A.; Irazu, Lucía E.; Romero, Graciela Noemi; Saraullo, Vanina Rosa; Watanabe, Olivia; Hamer, Micaela; Grune Loffler, Sylvia; Samartino, Luis Ernesto; Brihuega, Bibiana Felicitas (Elsevier, 2021-04)Leptospirosis is a zoonotic disease with worldwide endemicity in Argentina, it is a significant public health problem in low-income populations. Bovine leptospirosis is a serious economic problem for cattle production, ... -
Optimization and comparative analysis of LAMP and PCR techniques for the detection of leptospiral DNA in Golden Syrian hamsters
Hamer, Micaela; Watanabe, Olivia; Saraullo, Vanina Rosa; Ortega, Facundo Miguel; Sanchez, Maria Cristina; Martinez, Mara Leila; Brihuega, Bibiana Felicitas; Grune Loffler, Sylvia (Springer, 2024-03)Leptospirosis is a zoonotic disease with significant public health and economic impact worldwide. Rapid and accurate diagnosis is essential for effective prevention and treatment. This study optimized a loop-mediated ... -
Optimization and validation of LAMP technique for the detection of leptospiral DNA
Hamer, Micaela; Saraullo, Vanina Rosa; Esteban, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (International Leptospirosis Society, 2024-09)Leptospira spp. is the second most important abortifacient pathogen in livestock pro duction in Argentina, responsible for the loss of millions of dollars in the beef and dairy industry in the Pampas region (Cantón et al., ...