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Association between spoligotype-VNTR types and virulence of Mycobacterium bovis in cattle
Garbaccio, Sergio Gabriel; Macias, Analía; Shimizu, Ernesto; Paolicchi, Fernando; Pezzone, Natalia; Zapata, Laura; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Peyru, Maite; Caimi, Karina Cynthia; Zumarraga, Martin Jose; Canal, Ana María; Cataldi, Angel Adrian; Magnano, Gabriel (Taylor & Francis, 2014-01)Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that affects approximately 5% of Argentine cattle. The aim of this research was to study if it is possible to infer the degree of virulence of ... -
Bovine macrophages responses to the infection with virulent and attenuated Leptospira interrogans serovar Pomona
Nagel, Ariel Gaston; Vazquez, Cristina Lourdes; Etulain, Julia; Blanco, Federico Carlos; Gravisaco, María José; Gomez, Ricardo Martín; Caimi, Karina Cynthia (Elsevier, 2019-06)Leptospirosis is a zoonosis, caused by pathogenic spirochetes of the genus Leptospira. Although cattle are usually the maintenance hosts of serovar Hardjo, Pomona is the most frequent serovar circulating in Argentina. The ... -
Búsqueda de Leptospira spp. en visón americano Neogale vison (Schreber, 1777) en el sur de la provincia de Neuquén, Patagonia Argentina
Gozzi, Ana Cecilia; Caimi, Karina Cynthia; Piudo, Luciana; Rago, María Virginia; Monteverde, Martín; González, Alejandro; Guichón, Maria Laura (Sociedad Argentina para el Estudio de los Mamíferos, 2023)Los mamíferos domésticos y silvestres cumplen un rol importante en la epidemiología de la leptospirosis. El visón americano Neogale vison es un mustélido introducido en Argentina que podría actuar como portador/reservorio ... -
Desarrollo de inmunocromatografías para el diagnóstico de leptospirosis y neosporosis bovina
Montenegro, Valeria Noely; Varni, Vanina Delia; Nagel, Ariel Gaston; Jaramillo Ortiz, Jose Manuel; Paoletta, Martina; De La Fourniere, Sofia Ana María; Macoretta, Christian Leandro; Moore, Prando Dadin; Brihuega, Bibiana Felicitas; Caimi, Karina Cynthia; Wilkowsky, Silvina Elizabeth (2016)Los abortos en el ganado bovino implican pérdidas económicas en la industria pecuaria; los agentes infecciosos son una de las principales causas asociadas. Entre las diversas enfermedades identificadas en nuestro país como ... -
Epidemiología molecular y genómica comparativa de Leptospira spp. en Argentina
Varni, Vanina Delia (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2015-12)La leptospirosis es una enfermedad infecciosa causada por bacterias del género Leptospira y constituye una zoonosis de amplia distribución mundial. La enfermedad puede ser contraída a través del contacto con ambientes ... -
First Genome Sequence of Leptospira interrogans Serovar Pomona, Isolated from a Bovine Abortion
Varni, Vanina Delia; Koval, Ariel; Nagel, Ariel Gaston; Ruybal, Paula; Caimi, Karina Cynthia; Amadio, Ariel F. (2016)Leptospirosis is a widespread zoonosis and a re-emergent disease of global distribution with major relevance in veterinary pro- duction. Here, we report the whole-genome sequence of Leptospira interrogans serovar Pomona ... -
Genomic comparison of two strains of Mycobacterium avium subsp. paratuberculosis with contrasting pathogenic phenotype
Colombatti Olivieri, Maria Alejandra; Fresia, Pablo; Graña, Martín; Cuerda, Maria Ximena; Nagel, Ariel Gaston; Alvarado Pinedo, Maria Fiorella; Romano, Maria Isabel; Caimi, Karina Cynthia; Berná, Luisa; Santangelo, María De La Paz (Elsevier, 2023-01)In a previous study, we evaluated the degree of virulence of Mycobacterium avium subsp. paratuberculosis (Map) strains isolated from cattle in Argentina in a murine model. This assay allowed us to differentiate between ... -
Genotyping Mycobacterium bovis from cattle in the Central Pampas of Argentina: tempoal and regional trends
Shimizu, Ernesto; Macias, Analía; Paolicchi, Fernando; Magnano, Gabriel; Zapata, Laura; Fernandez, Analía; Canal, Ana María; Garbaccio, Sergio Gabriel; Cataldi, Angel Adrian; Caimi, Karina Cynthia; Zumarraga, Martin Jose (Fundacao Oswaldo Cruz, Brasil, 2014-04)Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a disease that affects approximately 5% of Argentinean cattle. Among the molecular methods for genotyping, the most convenient are spoligotyping and ... -
Isolation and clinical sample typing of human leptospirosis cases in Argentina
Varni, Vanina Delia; Caimi, Karina Cynthia; Jacob, Paulina; Chiani, Yosena; Landolt, Noelia; Schmeling, María Fernanda; Pujato, Nazarena; Vanasco, Bibiana (2016)Leptospira typing is carried out using isolated strains. Because of difficulties in obtaining them, direct identification of infective Leptospira in clinical samples is a high priority.Multilocus sequence typing (MLST) ... -
LAMP technology: Rapid identification of Brucella and Mycobacterium avium subsp. paratuberculosis
Trangoni, Marcos David; Gioffre, Andrea; Ceron Cucchi, Maria Esperanza; Caimi, Karina Cynthia; Ruybal, Paula; Zumarraga, Martin Jose; Cravero, Silvio Lorenzo Pedro (Sociedade Brasileira de Microbiologia, 2015-06)In this study, we developed new sets of primers to detect Brucella spp. and M. avium subsp. paratuberculosis (MAP) through isothermal amplification. We selected a previously well-characterized target gene, bscp31, specific ... -
Leptospira species molecular epidemiology in the genomic era
Caimi, Karina Cynthia; Repetto, Silvia A.; Varni, Vanina Delia; Ruybal, Paula (Elsevier, 2017-10)Leptospirosis is a zoonotic disease which global burden is increasing often related to climatic change. Hundreds of whole genome sequences from worldwide isolates of Leptospira spp. are available nowadays, together with ...