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Canarypox virus expressing infectious bursal disease VP2 protein as immunogen for chickens
Zanetti, Flavia Adriana; Conte Grand, María Daniela; Mitarotonda, Romina Cristina; Taboga, Oscar Alberto; Calamante, Gabriela (Sociedade Brasileira de Microbiologia, 2014-05)Canarypox viruses (CNPV) carrying the coding sequence of VP2 protein from infectious bursal disease virus (IBDV) were obtained. These viruses were able to express VP2 protein in vitro and to induce IBDV-neutralizing ... -
Induction of both local immune response in mice and protection in a rabbit model by intranasal immunization with modified vaccinia ankara virus expressing a secreted form of bovine herpesvirus 1 glycoprotein D
Del Medico Zajac, Maria Paula; Zanetti, Flavia Adriana; Federico, Carlos Rodolfo; Zabal, Osvaldo Alfredo; Valera, Alejandro Rafael; Calamante, Gabriela (2017)In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D ... -
Recombinant canarypox virus expressing the VP2 protein of infectious bursal disease virus induces protection in vaccinated SPF chickens
Zanetti, Flavia Adriana; Cardona, Romina; Federico, Carlos Rodolfo; Chimeno Zoth, Silvina Andrea; Calamante, Gabriela (2016)To study the in vivo distribution of the CNPV viral vector, we conducted two trials. In the first trial, six 11- day-old SPF chickens were intramuscularly vaccinated in one leg with CN048-VP2 (106 plaque-forming units ...