autores
- xmlui.general.dspace_homexmlui.ArtifactBrowser.ConfigurableBrowse.trail.metadata.author
- Inicio
- autores
Autores
Mostrando ítems 1-20 de 26
-
A safe and effective vaccine against bovine leukemia virus
Suarez Archilla, Guillermo; Gutierrez, Gerónimo; Camussone, Cecilia; Calvinho, Luis Fernando; Abdala, Alejandro Ariel; Alvarez, Irene; Petersen, Marcos; Franco, Lautaro Nahuel; De Stefano, Gabriel Alejandro; Monti, Gustavo; Jacques, Jean-Rock; Joris, Thomas; Willems, Luc; Trono, Karina Gabriela (Frontiers Media, 2022-08)Previous attempts to develop a vaccine against bovine leukemia virus (BLV) have not been successful because of inadequate or short-lived stimulation of all immunity components. In this study, we designed an approach based ... -
An efficient vaccine against bovine leukemia virus
Gutierrez, Gerónimo; Rodríguez, Sabrina M.; Vilor, Agustín; Gillet, Nicolas A.; DeBrogniez, Alix; Trono, Karina Gabriela; Willems, Luc (BioMed Central, 2015)Previous attempts to produce a vaccine against BLV faced problems of efficacy (i.e. only a fraction of animals were protected), persistence (i.e. rapid decrease of immune protection), cost (e.g. production of purified ... -
BLV: lessons on vaccine development
Abdala, Alejandro Ariel; Alvarez, Irene; Brossel, Hélène; Calvinho, Luis Fernando; Carignano, Hugo; Franco, Lautaro Nahuel; Gazon, Hélène; Gillissen, Christelle; Hamaidia, Malik; Hoyos, Clotilde; Jacques, Jean-Rock; Joris, Thomas; Laval, Florent; Petersen, Marcos Iván; Porquet, Florent; Porta, Natalia Gabriela; Ruiz, Vanesa; Safari, Rogaiyeh; Suarez Archilla, Guillermo Alejandro; Trono, Karina Gabriela; Willems, Luc (BMC, 2019-10-07)Vaccination against retroviruses is a challenge because of their ability to stably integrate into the host genome, undergo long-term latency in a proportion of infected cells and thereby escape immune response. Since ... -
BOLA-DRB3 gene polymorphisms influence bovine leukaemia virus infection levels in Holstein and Holstein × Jersey crossbreed dairy cattle
Carignano, Hugo Adrian; Beribe, Maria Jose; Caffaro, María Eugenia; Amadio, Ariel; Nani, Juan Pablo; Gutierrez, Gerónimo; Alvarez, Irene; Trono, Karina Gabriela; Miretti, Marcos Mateo; Poli, Mario Andres (2017-05)Bovine leukemia virus (BLV) infections, causing persistent lymphocytosis and lethal lymphosarcoma in cattle, have reached high endemicity on dairy farms. We observed extensive inter-individual variation in the level of ... -
Bovine leukemia virus becomes established in dairy herds before the first lactation
Merlini, Ramiro; Gutierrez, Gerónimo; Alvarez, Irene; Jaworski, Juan Pablo; Carignano, Hugo Adrian; Poli, Mario Andres; Willems, Luc; Trono, Karina Gabriela (2016)In this work, we studied seven groups of pregnant heifers from a consortium of dairy farms heavily infected with bovine leukemia virus (BLV). ELISA testing showed that the seroprevalence ranges of BLV in heifers between ... -
Bovine leukemia virus infection in neonatal calves. Risk factors and control measures
Ruiz, Vanesa; Porta, Natalia Gabriela; Lomonaco, Marina; Trono, Karina Gabriela; Alvarez, Irene (Frontiers Media, 2018-10)Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis (EBL). Although efficient eradication programs have been successfully implemented in most European countries and Oceania, BLV infection rates ... -
Bovine leukemia virus small noncoding RNAs are functional elements that regulate replication and contribute to oncogenesis in vivo
Gillet, Nicolas A.; Hamaidia, Malik; Brogniez, Alix de; Gutierrez, Gerónimo; Renotte, Nathalie; Reichert, Michal; Trono, Karina Gabriela; Willems, Luc (2016-04)Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) ... -
Characterization of colostrum from dams of BLV endemic dairy herds
Gutierrez, Gerónimo; Lomonaco, Marina; Alvarez, Irene; Fernandez, Fernando; Trono, Karina Gabriela (Elsevier, 2015-06)Bovine Leukemia Virus (BLV) is endemic in Argentina, where the individual prevalence is higher than 80% in dairy farms. The aim of this work was to find preliminary evidence to know if the high level of infection of the ... -
Detection of bovine leukemia virus RNA in blood samples of naturally infected dairy cattle
Alvarez, Irene; Porta, Natalia Gabriela; Trono, Karina Gabriela (MDPI, 2019-09)The viral expression in vivo, in bovine leukemia virus (BLV)-infected cattle, is considered to be restricted to extremely low levels, and the mitosis of infected B lymphocytes is regarded as the main mode of virus persistence ... -
Diagnóstico serológico de Leucosis Enzoótica Bovina en rodeos de cría de la provincia de Tierra del Fuego
Escribano, Cecilia Soledad; Disalvo, Vilma; Trono, Karina Gabriela (EEA Santa Cruz, INTA, 2016-02-12)La leucosis enzoótica bovina es una enfermedad infecciosa de curso crónico, de tipo neoplásica, que afecta al ganado bovino adulto, causada por un retrovirus, virus de la leucosis bovina, del género Deltaretrovirus en la ... -
Dynamics of perinatal bovine leukemia virus infection
Gutierrez, Gerónimo; Alvarez, Irene; Merlini, Ramiro; Rondelli, Flavia; Trono, Karina Gabriela (BioMed Central, 2014)Bovine leukemia virus (BLV) is highly endemic in many countries, including Argentina. As prevention of the spread from infected animals is of primary importance in breaking the cycle of BLV transmission, it is important ... -
The efficacy of ELISA commercial kits for the screening of equine infectious anemia virus infection = Eficacia de ensayos de ELISA comerciales para el screening de infección por el virus de la anemia infecciosa equina
Alvarez, Irene; Cipolini, Fabiana; Wigdorovitz, Andres; Trono, Karina Gabriela; Barrandeguy, Maria Edith (Elsevier España, 2015-03)The most used and reliable indicator of equine infectious anemia virus (EIAV) infection is the detection of its specific antibodies in horse serum. In the present study, the performance of two commercial ELISA tests for ... -
Efficacy of the spray-drying treatment to inactivate the bovine leukemia virus in bovine colostrum
Lomonaco, Marina; Sowul, Mariana; Gutierrez, Gerónimo; Malacari, Darío Amilcar; Alvarez, Irene; Porta, Natalia Gabriela; Zabal, Osvaldo Alfredo; Trono, Karina Gabriela (Elsevier, 2020-07)Previous studies have shown the presence of bovine leukemia virus (BLV) in colostrum and milk of naturally infected cows. The relationship between virus or provirus and specific antibodies in these secretions is particular ... -
Estudio del efecto del uso de anticuerpos específicos contra el virus de la leucosis bovina como suplemento dietario en terneros
Porta, Natalia Gabriela (Facultad de Ciencias Veterinarias, Universidad de Buenos Aires., 2018)En este trabajo se estudió el efecto del uso de anticuerpos de yema de huevo (IgY) anti BLV específicos como suplemento en la leche de consumo de terneros durante todo el período de cría, monitoreando a los animales desde ... -
Evaluation of total white blood cell count as a marker for proviral load of bovine leukemia virus in dairy cattle from herds with a high seroprevalence of antibodies against bovine leukemia virus
Alvarez, Irene; Gutierrez, Gerónimo; Gammella, Mariela; Martínez, Cecilia; Politzki, Romina Paula; González, Cintia Beatríz; Caviglia, Luciana; Carignano, Hugo; Fondevila, Norberto Antonio; Poli, Mario Andres; Trono, Karina Gabriela (2013-05)Objective—To determine the reference interval for WBC counts in Holstein dairy cows from herds with high seroprevalence for anti–bovine leukemia virus (BLV) antibodies, analyze the correlation of total WBC counts and blood ... -
Experimental infection of sheep with bovine leukemia virus (BLV): minimum dose of BLV-FLK cells and cell-free BLV and neutralization activity of natural antibodies = Infección experimental en ovinos con el virus de leucosis bovina: dosis mínima de células BLV-FLK y virus libre de células, y actividad neutralizante de anticuerpos naturales
Porta, Natalia Gabriela; Alvarez, Irene; Suarez Archilla, Guillermo Alejandro; Ruiz, Vanesa; Abdala, Alejandro Ariel; Trono, Karina Gabriela (Elsevier España, 2019-12)Bovine leukemia virus (BLV) is an important cattle pathogen that causes major economic losses worldwide, especially in dairy farms. The use of animal models provides valuable insight into the pathogenesis of viral infections. ... -
Expression-based analysis of genes related to single nucleotide polymorphism hits associated with bovine leukemia virus proviral load in Argentinean dairy cattle
Petersen, Marcos Iván; Carignano, Hugo Adrian; Suarez Archilla, Guillermo; Caffaro, María Eugenia; Alvarez, Irene; Miretti, Marcos Mateo; Trono, Karina Gabriela (Elsevier, 2021-02)In dairy cattle infected with bovine leukemia virus (BLV), the proviral load (PVL) level is directly related to the viral transmission from infected animals to their healthy herdmates. Two contrasting phenotypic groups can ... -
Genome-wide scan for commons SNPs affecting bovine leukemia virus infection level in dairy cattle
Carignano, Hugo Adrian; Roldan, Dana Leticia; Beribe, Maria Jose; Raschia, Maria Agustina; Amadio, Ariel; Nani, Juan Pablo; Gutierrez, Gerónimo; Alvarez, Irene; Trono, Karina Gabriela; Poli, Mario Andres; Miretti, Marcos Mateo (2018-02-13)Background: Bovine leukemia virus (BLV) infection is omnipresent in dairy herds causing direct economic losses due to trade restrictions and lymphosarcoma-related deaths. Milk production drops and increase in the culling ... -
Influencia de las condiciones de incubación en la detección de anticuerpos contra el Virus de la Leucosis bovina por ELISA = Influence of the incubation conditions on the detection of antibodies to bovine leukemia virus by ELISA
Lomonaco, Marina; Martinez, Cecilia; Alvarez, Irene; Gutierrez, Gerónimo; Politzki, Romina Paula; Trono, Karina Gabriela (Sociedad de Medicina Veterinaria, 2013-05)En este trabajo se modificaron las condiciones de incubación del ensayo de ELISAp24 que detecta anticuerpos contra el Virus de la Leucosis bovina, con el propósito de evaluar si se reduce el número de resultados falsos y ... -
Outbreak of Western equine encephalitis virus infection associated with neurological disease in horses following a nearly 40-year intermission period in Argentina
Vissani, Maria Aldana; Alamos, Florencia; Tordoya, Maria Silvia; Minatel, Leonardo; Schammas, Juan Manuel; Dus Santos, Maria Jose; Trono, Karina Gabriela; Barrandeguy, Maria Edith; Balasuriya, Udeni B.R.; Carossino, Mariano (MDPI, 2024-10)Western equine encephalitis virus (WEEV) is a mosquito-borne arbovirus (genus Alphavirus, family Togaviridae) that has re-emerged in South America in late 2023, causing severe disease in both horses and humans after a ...