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Aborto por Leptospira en una yegua en Salta, Argentina
Micheloud, Juan Francisco; Martinez, Mara Leila; Zurita, Sofía G.; Grune Loffler, Sylvia; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (2015)La leptospirosis en equinos es generalmente asintomática, aunque existen regiones donde la enfermedad constituye un problema. Aquí se describe un caso de aborto en yegua debido a la infección por este agente. Se efectuó ... -
Aislamiento de una cepa patógena de Leptospira spp del medio ambiente
Brihuega, Bibiana Felicitas; Hamer, Micaela; Esteban, Micaela; Saraullo, Vanina Rosa; Sanchez, Maria Cristina; Grune Loffler, Sylvia; Vilte, Daniel Alejandro; Martinez, Mara Leila (Universidad de Buenos Aires, 2025-10)La producción animal enfrenta nuevos desafíos relacionados con los riesgos potenciales de contaminación microbiológica del ambiente. La proximidad y concentración de animales favorece la transmisión de patógenos, y la ... -
Appication of loop-mediated isothermal amplification as a tool for environmental surveillance of leptospiral reservoirs
Hamer, Micaela; Saraullo, Vanina Rosa; Muschetto, Emiliano; Esteban, Micaela; Tripodi, Mariel Alejandra; Sanchez, Maria Cristina; Hancke, Diego; Suárez, Olga Virginia; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Sociedad Argentina de Microbiología General, 2025-08)Leptospirosis is a globally important zoonosis caused by pathogenic strains of the genus Leptospira, affecting domestic and wild animals as well as humans. The survival of leptospires in the environment plays a key role ... -
Biofilm formation by Aquaspirillum spp. and saprophytic Leptospira spp. isolated from environmental source of Argentine
Scialfa, Exequiel; Videla, Yanina; Grune Loffler, Sylvia; Quintana, Silvina; Aguirre, Pablo; Brihuega, Bibiana Felicitas (Faculty of Biotechnology and Food Sciences, Slovakia, 2019-07)Leptospirosis is a zoonotic disease of global distribution, caused by bacteria of the genus Leptospira. These spirochetes are living organisms free of mud and water; pathogenic leptospires can survive several days in fresh ... -
Comparison of ELISA using recombinant LipL32 and sonicated antigen of leptospira for detecting bovine leptospirosis
Martinez, Mara Leila; Rodriguez, Marcelo A.; Saraullo, Vanina Rosa; Irazu, Lucía E.; Hamer, Micaela; Watanabe, Olivia; Grune Loffler, Sylvia; Romero, Graciela Noemi; Samartino, Luis Ernesto; Brihuega, Bibiana Felicitas (Elsevier, 2022-01)Leptospirosis is one of the most widely distributed zoonosis in the world. Bovine leptospirosis is a serious problem in bovine production, causing reproductive losses. The aim of this work was to compare recombinant LipL32 ... -
Desarrollo de inmunocromatografías para el diagnóstico de leptospirosis y neosporosis bovina
Montenegro, Valeria Noely; Varni, Vanina Delia; Nagel, Ariel Gaston; Jaramillo Ortiz, Jose Manuel; Paoletta, Martina; De La Fourniere, Sofia Ana María; Macoretta, Christian Leandro; Moore, Prando Dadin; Brihuega, Bibiana Felicitas; Caimi, Karina Cynthia; Wilkowsky, Silvina Elizabeth (2016)Los abortos en el ganado bovino implican pérdidas económicas en la industria pecuaria; los agentes infecciosos son una de las principales causas asociadas. Entre las diversas enfermedades identificadas en nuestro país como ... -
Detección de Leptospira spp. (Spirochaetales: Leptospiraceae) en muestras ambientales de regiones habitadas por poblaciones vulnerables del norte argentino
Grune Loffler, Sylvia; Periago, María Victoria; Watanabe, Olivia; Saraullo, Vanina Rosa; Aldama, Evangelina; Cejas, Graciela; Cruz, Diego; Delgado, Cintia; Goizueta, Carolina; Hamer, Micaela; Martinez, Mara Leila; Brihuega, Bibiana Felicitas (Facultad de Ciencias Veterinarias, Universidad Nacional del Litoral, 2021-12)La leptospirosis continúa siendo hoy en día un problema para la salud pública, principalmente en poblaciones de bajos recursos socioeconómicos. En este trabajo se presenta la detección de leptospiras patógenas en muestras ... -
Detection of antibodies against Brucella abortus, Leptospira spp., and Apicomplexa protozoa in water buffaloes in the Northeast of Argentina
Konrad, Jose Luis; Campero, Lucía María; Caspe, Sergio Gaston; Brihuega, Bibiana Felicitas; Draghi, Maria Graciela; Moore, Prando Dadin; Crudeli, Gustavo Angel; Venturini, María Cecilia; Campero, Carlos Manuel (2013-11)Water buffalo industry has become a profitable activity worldwide, including the Northeast of Argentina (NEA). However, research on diseases affecting this species is scarce. The aim of the present study was to detect ... -
Detection of leptospiral antibodies in wild animals in aquatic environments of Argentina
Brihuega, Bibiana Felicitas; Saraullo, Vanina Rosa; Hamer, Micaela; Esteban, Micaela; Sanchez, Maria Cristina; Samartino, Luis Ernesto; Martinez, Mara Leila (International Leptospirosis Society, 2024-09)Zoonoses are defined as diseases of animals that are transmitted naturally to hu mans, directly or indirectly. Indirect transmission can manifest itself through the pres ence of these pathogens in the environment. The ... -
Diagnosis of canine leptospirosis: evaluation of two PCR assays in comparison with the microagglutination test = Diagnóstico de leptospirose canina: avaliação de dois ensaios de PCR em comparação com o teste de microaglutinação
Martin, Paula L.; Stanchi, Nestor O.; Brihuega, Bibiana Felicitas; Bonzo, Estela; Galli, Lucía; Arauz, María S. (Colegio Brasileiro de Patologia Animal, 2019-04)Canine leptospirosis is definitely diagnosed by demonstrating seroconversion in paired serum samples from the acute and convalescent period by the microagglutination test (MAT). However, the application of a polymerase ... -
Diferenciación de serovares de leptospiras patógenas mediante PCR del gen ligB y secuenciación = Differentiation of pathogenic leptospires spp by PCR of ligB gene and sequencing
Martinez, Mara Leila; Grune Loffler, Sylvia; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (Asociación Argentina de Microbiología, 2018)La leptospirosis es la zoonosis de mayor distribución mundial. El objetivo del presente trabajo fue desarrollar una técnica molecular que diferencie leptospiras patógenas. Se amplificó mediante PCR y se secuenció una ... -
Discriminación genotípica de serovariedades del serogrupo Icterohaemorrhagiae pertenecientes a Leptospira interrogans (Spirochaetales: Leptospiraceae) y el análisis de distancias génicas mediante coordenadas principales
Grune Loffler, Sylvia; Martinez, Mara Leila; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (2017-01-18)La leptospirosis es una zoonosis de amplia distribución mundial y de importancia en salud pública y veterinaria. El serogrupo Icterohaemorrhagiae toma importancia, ya que ha sido aislado con frecuencia en roedores y en ... -
Discriminación genotípica de serovariedades del serogrupo Icterohaemorrhagiae pertenecientes a Leptospira interrogans (Spirochaetales: Leptospiraceae) y el análisis de distancias génicas mediante coordenadas principales = Genotypic discrimination of serovars belonging to the serogroup Icterohaemorrhagiae of Leptospira interrogans (Spirochaetales: Leptospiraceae) and the analysis of genetic distances using principal coordinates
Grune Loffler, Sylvia; Martinez, Mara Leila; Romero, Graciela Noemi; Brihuega, Bibiana Felicitas (Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias, 2016)La leptospirosis es una zoonosis de amplia distribución mundial y de importancia en salud pública y veterinaria. El serogrupo Icterohaemorrhagiae toma importancia, ya que ha sido aislado con frecuencia en roedores y en ... -
Enhanced detection of Leptospira in cattle : Comparative performance of loop-mediated isothermal amplification, polymerase chain reaction and serological methods
Hamer, Micaela; Saraullo, Vanina Rosa; Esteban, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Elsevier, 2025-09)Leptospirosis is a globally distributed zoonotic disease. This study aimed to evaluate the performance of loop-mediated isothermal amplification (LAMP) in detecting Leptospira DNA in bovine samples compared to conventional ... -
Evaluation of LigB polymerase chain reaction as a complementary tool to microscopic agglutination test for the detection of bovine leptospirosis in serum samples
Saraullo, Vanina Rosa; Hamer, Micaela; Esteban, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (Elsevier, 2025-05)Leptospirosis is a significant infectious disease affecting livestock. Microscopic agglutination test (MAT) is used as the gold standard; however, the inclusion of molecular tools (PCR) could improve the accuracy of ... -
First isolation of Leptospira borgpetersenii from Fetuses of Wild boars (Sus scrofa)
Brihuega, Bibiana Felicitas; Grune Loffler, Sylvia; Samartino, Luis Ernesto; Romero, Graciela Noemi; Auteri, Carmelo Domingo; Martinez, Mara Leila (2017-02-07)Leptospirosis is a worldwide zoonose and is endemic in many countries. This zoonosis is maintained in nature by chronic renal infection of carrier animals, being rodents and other small mammals the most important reservoirs. ... -
First isolation of Leptospira interrogans from the arboreal squirrel Callosciurus erythraeus introduced in Argentina
Gozzi, Ana Cecilia; Guichon, Maria Laura; Benitez, Verónica Victoria; Romero, Graciela Noemi; Auteri, Carmelo Domingo; Brihuega, Bibiana Felicitas (Bioone, 2013-12-01)We isolated Leptospira strains from renal tissue samples of Asiatic red-bellied squirrels Callosciurus erythraeus, captured in Argentina. In December 2008, we captured 34 squirrels in the province of Santa Fe during a short ... -
First record of the presence of antibodies against Leptospira in Lagostomus maximus, and Leptospira weillii serogroup Celledoni in Chaetophractus villosus, Argentina
Kin, Marta Susana; Sanchez, Maria Cristina; Esteban, Micaela; Martinez, Mara Leila; Brihuega, Bibiana Felicitas; Hamer, Micaela; Saraullo, Vanina Rosa; Cayron, Eduardo D.; Cayron, Gabriel P.; Gimenez, Hugo Daniel; Cayron, Carlos R.; Fort, Marcelo Cristian (Elsevier, 2025-03)Leptospirosis is a zoonosis with a worldwide distribution, which is transmitted through direct contact with infected animals or by contact with contaminated water or soil. Objectives was to examine the presence of antibodies ... -
First report of pathogenic Leptospira spp. in Tadarida brasiliensis bats (family Molossidae) and Eptesicus furinalis (family Vespertilionidae) of Argentina. New host species in this country? = Primer reporte de Leptospira spp. patógena en murciélagos Tadarida brasiliensis (familia: Molossidae) y Eptesicus furinalis (familia: Vespertilionidae) en Argentina. ¿Nuevas especies hospedadoras en el país?
Saraullo, Vanina Rosa; Grune Loffler, Sylvia; Pastorino, Florencia; Watanabe, Olivia; Alonso, Maria Laura; Hamer, Micaela; Moreira, Cecilia; Martinez, Mara Leila; Martinez, Gustavo; Brihuega, Bibiana Felicitas (Elsevier, 2021-09)Leptospirosis is an endemic disease caused by Leptospira spp., a bacterium that affects animals and humans. In recent years, the number of reports of leptospirosis in wild animals has increased, which highlights the need ... -
In silico evaluation of Lipl32 peptides for antigen candidates in leptospirosis diagnostic
Esteban, Micaela; Saraullo, Vanina Rosa; Madero, Agustin; Hamer, Micaela; Sanchez, Maria Cristina; Brihuega, Bibiana Felicitas; Martinez, Mara Leila (International Leptospirosis Society, 2024-09)Leptospirosis is a zoonotic infectious disease caused by the spirochete of the genus Leptospira. The gold-standard technique for diagnosis is the microscopic agglutina tion test, however, this serological test is complex ...