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A comprehensive analysis of the genetic diversity and environmental adaptability in worldwide Merino and Merino‑derived sheep breeds
Ceccobelli, Simone; Landi, Vincenzo; Senczuk, Gabriele; Mastrangelo, Salvatore; Sardina, Maria Teresa; Ben‑Jemaa, Slim; Persichilli, Christian; Karsli, Taki; Balteanu, Valentin‑Adrian; Raschia, Maria Agustina; Poli, Mario Andres; Ciappesoni, Gabriel; Muchadeyi, Farai Catherine; Dzomba, Edgar Farai; Kunene, Nokuthula Winfred; Lühken, Gesine; Deniskova, Tatiana Evgenievna; Dotsev, Arsen Vladimirovich; Zinovieva, Natalia Anatolievna; Zsolnai, Attila; Anton, István; Kusza, Szilvia; Carolino, Nuno; Santos‑Silva, Fátima; Kawęcka, Aldona; Swiatek, Marcin; Niżnikowski, Roman; Spehar, Marija; Anaya, Gabriel; Granero, Antonio; Perloiro, Tiago; Cardoso, Pedro; Grande, Silverio; López de los Santos, Beatriz; Danchin‑Burge, Coralie; Pasquini, Marina; Martínez Martínez, Amparo; Delgado Bermejo, Juan Vicente; Lasagna, Emiliano; Ciani, Elena; Sarti, Francesca Maria; Pilla, Fabio (BioMed Central, 2023-04)Background: To enhance and extend the knowledge about the global historical and phylogenetic relationships between Merino and Merino-derived breeds, 19 populations were genotyped with the OvineSNP50 BeadChip specifically ... -
Análisis de la duración de la gestación y de los loci que influyen sobre ella en bovinos Holando y cruzas
Raschia, Maria Agustina; Maizon, Daniel Omar; Poli, Mario Andres (Asociación Argentina de Producción Animal, 2022-11)Introducción: La intensa selección para producción lechera junto con una consideración insuficiente de parámetros de fertilidad y salud va en detrimento de estos últimos rasgos. Muchos países ampliaron los objetivos de sus ... -
Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats
Rossi, Ursula; Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Raschia, Maria Agustina; Maurizio, Estefania; Cortez, Hector Sergio; Neumann, Roberto Daniel; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2019-03)Brucellosis is an important zoonotic disease caused by infection with Brucella spp. It generates major economic losses in livestock production worldwide. Goats are the principal hosts of B. melitensis, the main infection ... -
Association of TNF rs668920841 and INRA111 polymorphisms with caprine brucellosis: A case-control study of candidate genes involved in innate immunity
Hasenauer, Flavia Carolina; Rossi, Ursula; Caffaro, María Eugenia; Raschia, Maria Agustina; Maurizio, Estefanía; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2020-11)Caprine brucellosis is an infectious, contagious zoonotic disease caused by Brucella melitensis. Multiple factors, including host genetics, can influence the outcome of the exposure to Brucella; and it is expected that ... -
Dataset from: “Frequencies of β-casein variants and their influence on genetic merit for production traits in Holstein cows [Conjunto de datos]
Caffaro, María Eugenia; Raschia, Maria Agustina; Maizon, Daniel Omar; Poli, Mario Andres (2024)The dataset consists of records from 2600 Holstein cows from three private farms in the central dairy area of Argentina with different breeding objectives and phenotypic records taken over different seasons, periods, and ... -
Deletion in KARLN intron 5 and predictive relationship with bovine tuberculosis and brucellosis infection phenotype
Rossi, Ursula Amaranta; Caffaro, María Eugenia; Raschia, Maria Agustina; Hasenauer, Flavia Carolina; Poli, Mario Andres; Rossetti, Carlos Alberto (Springer, 2023-06)Kalirin (gene: KALRN) is a Rho-GEF kinase linked to neurodegenerative diseases in humans. Unexpectedly, various polymorphisms in KALRN gene were previously associated with resistance to bacterial infections in ruminants. ... -
Desequilibrio de ligamiento en cromosomas con genes candidatos para calidad de lana en ovinos Corriedale
Cordoba, Marcela Elisabet; Raschia, Maria Agustina; Donzelli, María Valeria; Cetra, Bibiana Maria; Medus, Pablo Daniel; Bonelli, Rita; Caffaro, María Eugenia; Maizon, Daniel Omar; Poli, Mario Andres (INTA, 2024-11)Los enfoques moleculares para la selección permiten explotar el potencial genético de especies productoras de fibra, incorporando evaluaciones genómicas en programas de cría. Numerosos genes afectan la expresión de ... -
Estudio de variables biológicas ante un desafío artificial de L3 de H. contortus en dos majadas de ovinos Corriedale
Donzelli, María Valeria; Maizon, Daniel Omar; Cetra, Bibiana Maria; Medus, Pablo Daniel; Bonelli, Rita; Raschia, Maria Agustina; Caffaro, María Eugenia; Poli, Mario Andres (Asociación Argentina de Producción Animal, 2022-11)H. contortus es uno de los parásitos que ocasiona mayores problemas en regiones templadas, tropicales y subtropicales debido a pérdidas productivas y económicas. La utilización de drogas es fundamental para el control de ... -
Frequencies of β-casein variants and their influence on genetic merit for production traits in Holstein cows
Caffaro, María Eugenia; Raschia, Maria Agustina; Maizon, Daniel Omar; Poli, Mario Andres (CSIRO Publishing, 2024-12)Context: Traits considered for selection are influenced by social, consumer, and breeder demands. In the past decades, there has been increasing global interest in producing milk free from the β-casein (CSN2) A1 allele ... -
Generalized glycogenosis in Brahman-derived breeds: diagnosis and prevalence in Argentina
Caffaro, María Eugenia; Raschia, Maria Agustina; Amadio, Ariel; Poli, Mario Andres (Springer, 2019-08)Generalized glycogenosis is a lethal autosomal recessive disease caused by a deficient activity of the acidic 1,4-α-glucosidase enzyme and characterized by an accumulation of glycogen within lysosomes. Three mutations in ... -
Genetic resistance to gastrointestinal parasites in sheep
Poli, Mario Andres; Donzelli, María Valeria; Caffaro, María Eugenia; Raschia, Maria Agustina; Papaleo Mazzucco, Juliana; Rossi, Ursula Amaranta (CAB International, 2023-06)Gastrointestinal nematode (GIN) infection is the most common disease affecting sheep production systems throughout the world, causing significant productive and economic losses. The control of these parasites was traditionally ... -
Genome-wide association study for somatic cell score in Argentinean dairy cattle
Nani, Juan Pablo; Raschia, Maria Agustina; Poli, Mario Andres; Calvinho, Luis Fernando; Amadio, Ariel (2015-05)This study aimed to understand the genomic architecture of Argentinean dairy herds by measuring linkage disequilibrium (LD) and identifying loci associated with parameters calculated from somatic cell count (SCC). Phenotypic ... -
Genome-wide scan for commons SNPs affecting bovine leukemia virus infection level in dairy cattle
Carignano, Hugo Adrian; Roldan, Dana Leticia; Beribe, Maria Jose; Raschia, Maria Agustina; Amadio, Ariel; Nani, Juan Pablo; Gutierrez, Gerónimo; Alvarez, Irene; Trono, Karina Gabriela; Poli, Mario Andres; Miretti, Marcos Mateo (2018-02-13)Background: Bovine leukemia virus (BLV) infection is omnipresent in dairy herds causing direct economic losses due to trade restrictions and lymphosarcoma-related deaths. Milk production drops and increase in the culling ... -
Genotipificación de variantes de beta-caseína bovina mediante ACRSPCR- RFLP = Genotyping of bovine beta-casein variants by ACRS-PCR-RFLP
Caffaro, María Eugenia; Raschia, Maria Agustina; Poli, Mario Andres (Consejo de Rectores de Universidades Privadas, 2023-10)Las variantes de la beta-caseína bovina pueden clasificarse en dos grupos, tipo-A1 y tipo-A2, según el aminoácido que esté presente en la posición 67 de la proteína (His, tipo A1; Pro, tipo A2)1. En los últimos años se ha ... -
Identificación de variantes alélicas de genes candidatos involucrados en producción de leche en un rodeo de bovinos de raza Holando y cruzas Holando por Jersey
Raschia, Maria Agustina (Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2015-07)Las razas bovinas Holando y Jersey son dos de las razas productoras de leche más importantes a nivel mundial y las principales en nuestro país. El objetivo del trabajo de tesis fue realizar un análisis exploratorio que ... -
Imputación de genotipos faltantes mediante algoritmos de machine learning = Imputation of missing genotypes using machine learning algorithms
Raschia, Maria Agustina; Rios, Pablo Javier; Cordoba, Marcela Elisabet; Caffaro, María Eugenia; Donzelli, María Valeria; Maizon, Daniel Omar; Demitrio, Daniel Arturo; Poli, Mario Andres (Sociedad Argentina de Informática e Investigación Operativa (SADIO), 2025-08)Resumen. La imputación o inferencia de genotipos faltantes utilizando correlaciones entre variantes obtenidas a partir de paneles de referencia puede ser llevada a cabo por programas específicos basados en la utilización ... -
Integrating technologies for the sustainable control of gastrointestinal parasites in sheep : The Argentinean case
Poli, Mario Andres; Caffaro, María Eugenia; Cetra, Bibiana Maria; Pichler, Rudolf; Raschia, Maria Agustina; Medus, Pablo Daniel; Maizon, Daniel Omar; Garcia Podesta, Mario; Donzelli, María Valeria; Bonelli, Rita; Periasamy, Kathiravan (FAO, 2023)Gastrointestinal nematode infections in sheep are a major concern among breeders due to the economic losses they cause in terms of a reduction in both productivity and viability of animals. The situation worsens in face ... -
Loci de caracteres cuantitativos para rasgos reproductivos en bovinos lecheros locales
Raschia, Maria Agustina; Maizon, Daniel Omar; Amadio, Ariel; Poli, Mario Andres (Sociedad Argentina de Genética, 2022-10)Introducción: La intensa selección para producción lechera junto con una consideración insuficiente de parámetros de fertilidad y salud, sumado a las correlaciones genéticas antagonistas o cercanas a cero entre caracteres ... -
Machine learning algorithms identified relevant SNPs for milk fat content in cattle
Ríos, Pablo J.; Raschia, Maria Agustina; Maizon, Daniel Omar; Demitrio, Daniel Arturo; Poli, Mario Andres (Sociedad Argentina de Informática, 2021-10)In recent years, machine learning methods have been shown to be efficient in identifying a subset of single nucleotide polymorphisms (SNP) underlying a trait of interest. The aim of this study was the construction of ... -
Methodology for the identification of relevant loci for milk traits in dairy cattle, using machine learning algorithms
Raschia, Maria Agustina; Ríos, Pablo Javier; Maizon, Daniel Omar; Demitrio, Daniel Arturo; Poli, Mario Andres (Elsevier, 2022)Machine learning methods were considered efficient in identifying single nucleotide polymorphisms (SNP) underlying a trait of interest. This study aimed to construct predictive models using machine learning algorithms, to ...