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A safe and effective vaccine against bovine leukemia virus
Suarez Archilla, Guillermo; Gutierrez, Gerónimo; Camussone, Cecilia; Calvinho, Luis Fernando; Abdala, Alejandro Ariel; Alvarez, Irene; Petersen, Marcos; Franco, Lautaro Nahuel; De Stefano, Gabriel Alejandro; Monti, Gustavo; Jacques, Jean-Rock; Joris, Thomas; Willems, Luc; Trono, Karina Gabriela (Frontiers Media, 2022-08)Previous attempts to develop a vaccine against bovine leukemia virus (BLV) have not been successful because of inadequate or short-lived stimulation of all immunity components. In this study, we designed an approach based ... -
Antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis: Systematic review and meta-analysis
Molineri, Ana Ines; Camussone, Cecilia; Zbrun, María Virginia; Suarez Archilla, Guillermo; Cristiani, Mariana; Neder, Veronica Elizabeth; Calvinho, Luis Fernando; Signorini Porchiett, Marcelo Lisandro (Elsevier, 2021-03)Staphylococcus aureus, one of the main contagious mastitis pathogens worldwide, is characterized for causing chronic intramammary infections that respond poorly to antimicrobial therapy, disseminating within the herd leading ... -
Antimicrobial resistance of Streptococcus uberis isolated from bovine mastitis: Systematic review and meta-analysis
Miotti, Camila; Cicotello, Joaquin; Suarez Archilla, Guillermo; Neder, Veronica Elizabeth; Alvarado, Wanda; Calvinho, Luis Fernando; Signorini Porchiett, Marcelo Lisandro; Camussone, Cecilia; Zbrun, María Virginia; Molineri, Ana Ines (Elsevier, 2023-11)Streptococcus uberis is one of the most common pathogens associated with bovine mastitis, commonly treated with antimicrobials (AM), favoring the appearance of antimicrobial resistance (AMR). The objective of this work was ... -
BLV: lessons on vaccine development
Abdala, Alejandro Ariel; Alvarez, Irene; Brossel, Hélène; Calvinho, Luis Fernando; Carignano, Hugo; Franco, Lautaro Nahuel; Gazon, Hélène; Gillissen, Christelle; Hamaidia, Malik; Hoyos, Clotilde; Jacques, Jean-Rock; Joris, Thomas; Laval, Florent; Petersen, Marcos Iván; Porquet, Florent; Porta, Natalia Gabriela; Ruiz, Vanesa; Safari, Rogaiyeh; Suarez Archilla, Guillermo Alejandro; Trono, Karina Gabriela; Willems, Luc (BMC, 2019-10-07)Vaccination against retroviruses is a challenge because of their ability to stably integrate into the host genome, undergo long-term latency in a proportion of infected cells and thereby escape immune response. Since ... -
Detección de anticuerpos anti-Mycobacterium bovis en sangre y calostro bovino
Ruiz Menna, Victoria Aymara; Garro, Carlos Javier; Felippa, E.; Abdala, Alejandro Ariel; Suarez Archilla, Guillermo; Sammarruco, Romina Ayelén; Delgado, Fernando Oscar; Garbaccio, Sergio Gabriel (Universidad Nacional del Centro de la Provincia de Buenos Aires, 2023-08)La tuberculosis bovina (TB) es una enfermedad endémica causada principalmente por Mycobacterium bovis. La respuesta inmune es predominantemente celular, siendo la intradermorreacción (IDR) la prueba diagnóstica de referencia. ... -
Efficacy of immunization with a recombinant S. aureus vaccine formulated with liposomes and ODN-CpG against natural S. aureus intramammary infections in heifers and cows
Camussone, Cecilia; Reidel, Ivana Gabriela; Molineri, Ana Ines; Cicotello, Joaquin; Miotti, Camila; Suarez Archilla, Guillermo; Curti, C.C.; Veaute, Carolina Melania Isabel; Calvinho, Luis Fernando (Elsevier, 2022-07)The aims of the present study were to evaluate the ability of a subunit vaccine composed of recombinant molecules of α-toxin, β-toxin, FnBPA and ClfA, formulated with cationic liposomes and CpG-ODN, to confer protection ... -
Eficacia del monepantel para el control de aislamientos de Haemonchus contortus y Trichostrongylus spp. con resistencia múltiple (ivermectina y febendazole) en caprinos
Cooper, Laura G.; Cerutti, Julieta; Mohn, Cristian Antonio; Torrents, Jorgelina; Suarez Archilla, Guillermo Alejandro; Anziani, Oscar Sergio (Facultad de Ciencias Veterinarias de Esperanza, Universidad Nacional del Litoral, 2016)El monepantel es un nuevo antihelmíntico registrado en nuestro país exclusivamente para el control de los nematodes gastrointestinales de los ovinos y su uso ha sido direccionado mayormente hacia el control de parásitos ... -
Eficacia reducida de derquantel y abamectina en ovinos y caprinos con Haemonchus sp resistentes a lactonas macrocíclicas
Cerutti, Julieta; Cooper, Laura G.; Torrents, Jorgelina; Suarez Archilla, Guillermo Alejandro; Anziani, Oscar Sergio (2018)Se presentan las observaciones efectuadas sobre la actividad de una combinación antihelmíntica conteniendo un nueva droga, el derquantel (spiroindoles) adicionada con abamectina (lactonas macrocíclicas) en ovinos y caprinos ... -
Experimental infection of sheep with bovine leukemia virus (BLV): minimum dose of BLV-FLK cells and cell-free BLV and neutralization activity of natural antibodies = Infección experimental en ovinos con el virus de leucosis bovina: dosis mínima de células BLV-FLK y virus libre de células, y actividad neutralizante de anticuerpos naturales
Porta, Natalia Gabriela; Alvarez, Irene; Suarez Archilla, Guillermo Alejandro; Ruiz, Vanesa; Abdala, Alejandro Ariel; Trono, Karina Gabriela (Elsevier España, 2019-12)Bovine leukemia virus (BLV) is an important cattle pathogen that causes major economic losses worldwide, especially in dairy farms. The use of animal models provides valuable insight into the pathogenesis of viral infections. ... -
Expression-based analysis of genes related to single nucleotide polymorphism hits associated with bovine leukemia virus proviral load in Argentinean dairy cattle
Petersen, Marcos Iván; Carignano, Hugo Adrian; Suarez Archilla, Guillermo; Caffaro, María Eugenia; Alvarez, Irene; Miretti, Marcos Mateo; Trono, Karina Gabriela (Elsevier, 2021-02)In dairy cattle infected with bovine leukemia virus (BLV), the proviral load (PVL) level is directly related to the viral transmission from infected animals to their healthy herdmates. Two contrasting phenotypic groups can ... -
Guía para el control de los parásitos externos en bovinos de leche del área central de la Argentina
Anziani, Oscar Sergio; Suarez Archilla, Guillermo Alejandro (Ediciones INTA, 2017)La Guía para el control de los parásitos externos en bovinos de leche del área central de la Argentina sintetiza la información actualmente disponible sobre el control de los parásitos externos de mayor importancia económica ... -
Guía para el control de los parásitos externos en bovinos de leche del área central de la Argentina : 02
Anziani, Oscar Sergio; Suarez Archilla, Guillermo Alejandro (Ediciones INTA, 2017)La Guía para el control de los parásitos externos en bovinos de leche del área central de la Argentina sintetiza la información actualmente disponible sobre el control de los parásitos externos de mayor importancia económica ... -
Liposomal and CpG-ODN formulation elicits strong humoral immune responses to recombinant Staphylococcus aureus antigens in heifer calves
Reidel, Ivana Gabriela; Camussone, Cecilia; Suarez Archilla, Guillermo Alejandro; Calvinho, Luis Fernando; Veaute, Carolina Melania Isabel (Elsevier, 2019-05-01)Bovine mastitis caused by Staphylococcus aureus is a serious problem in dairy production and effective immunoprophylaxis is an unmet goal so far. The objective of this work was to assess the humoral immune response of ... -
Monepatel y control de Haemonchus contortus en ovinos. Evaluación de la eficacia luego de cuatro años de uso en condiciones de refugio reducido
Torrents, Jorgelina; Suarez Archilla, Guillermo Alejandro; Anziani, Oscar Sergio (2015-04)La resistencia de los nematodes ovinos a los antihelmínticos está generalizada en el centro-norte de la Argentina y la mayor preocupación actual es el aumento y dispersión de Haemonchus contortus portando alelos con ... -
Seroprevalence and risk factors associated with bovine Leukemia virus infection in argentine beef cattle
Porta, Natalia Gabriela; Suarez Archilla, Guillermo; Miotti, Camila; Molineri, Ana Ines; Alvarez, Irene; Trono, Karina Gabriela; Signorini Porchiett, Marcelo Lisandro; Ruiz, Vanesa (Elsevier, 2023-11)Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis, an endemic disease in dairy cattle of Argentina. However, little is known about the seroprevalence of BLV in beef cattle. In this study, we ...