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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
Richetta, Matias Daniel; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Gravisaco, María José; Calamante, Gabriela; Berinstein, Analia (2017-01)Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ... -
Immunomodulatory effect of baculovirus in chickens : how it modifies the immune response against infectious bursal disease virus
Chimeno Zoth, Silvina Andrea; Carballeda, Juan Manuel; Gravisaco, María José; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Berinstein, Analia (2016)Several reports have shown that baculoviruses (BVs) have strong adjuvant properties on the mammalian immune system. Recent studies of our group demonstrated the ability of BV to stimulate the innate immunity in chickens. ... -
Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein
Carballeda, Juan Manuel; Maroniche, Guillermo Andrés; Lucero, Maria Soledad; Richetta, Matias Daniel; Gomez, Evangelina Raquel; Chimeno Zoth, Silvina Andrea; Berinstein, Analia (Elsevier, 2015-09)Infectious Bursal Disease Virus (IBDV) causes a highly relevant poultry disease that affects young chickens causing, among other effects, immunosuppression. IBDV is a bi-segmented double stranded RNA virus. The smaller ORF ... -
Plant-based vaccine candidate against Infectious bursal disease: an alternative to inactivated vaccines for breeder hens
Lucero, Maria Soledad; Richetta, Matias Daniel; Chimeno Zoth, Silvina Andrea; Jaton, Juan; Pinto, Silvina; Canet, Zulma Edith; Berinstein, Analia; Gomez, Evangelina Raquel (Elsevier, 2019-08)Infectious bursal disease (IBD) is an acute, highly contagious immunosuppressive disease that affects young birds causing important economic losses in the poultry industry worldwide. Strict hygiene management together with ...