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Anthropogenic infection of domestic cats with SARS-CoV-2 alpha variant B.1.1.7 lineage in Buenos Aires
Pecora, Andrea; Malacari, Darío Amilcar; Mozgovoj, Marina Valeria; Díaz, María de los Ángeles; Peralta, Andrea Veronica; Cacciabue, Marco Polo Domingo; Puebla, Andrea Fabiana; Carusso, Cristian; Mundo, Silvia Leonor; Gonzalez Lopez Ledesma, María Mora; Gamarnik, Andrea Vanesa; Rinaldi, Osvaldo; Vidal, Osvaldo; Mas, Javier; Dus Santos, Maria Jose (Frontiers Media, 2022-03)SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the ... -
Development of an APC-targeted multivalent E2-based vaccine against Bovine Viral Diarrhea Virus types 1 and 2
Pecora, Andrea; Malacari, Darío Amilcar; Pérez Aguirreburualde, María Sol; Bellido, Demian; Nuñez, Maria del Carmen; Dus Santos, Maria Jose; Martínez Escribano, José Angel; Wigdorovitz, Andres (Elsevier, 2015-09)The aim of this study was to develop and test a multivalent subunit vaccine against Bovine Viral Diarrhea Virus (BVDV) based on the E2 virus glycoprotein belonging to genotypes 1a, 1b and 2a, immunopotentiated by targeting ... -
Early Adaptive Immune Responses in the Respiratory Tract of Foot-and-Mouth Disease Virus-Infected Cattle
Pega, Juan Franco; Bucafusco, Danilo; Di Giacomo, Sebastián; Schammas, Juan Manuel; Malacari, Darío Amilcar; Capozzo, Alejandra Victoria; Arzt, J.; Pérez-Beascoechea, C.; Maradei, E.; Rodríguez, L.L.; Borca, Manuel Victor; Perez Filgueira, Daniel Mariano (2013-03)Foot-and-mouth disease (FMD) is a highly contagious viral disease which affects both domestic and wild biungulate species. This acute disease, caused by the FMD virus (FMDV), usually includes an active replication phase ... -
Efficacy of the spray-drying treatment to inactivate the bovine leukemia virus in bovine colostrum
Lomonaco, Marina; Sowul, Mariana; Gutierrez, Gerónimo; Malacari, Darío Amilcar; Alvarez, Irene; Porta, Natalia Gabriela; Zabal, Osvaldo Alfredo; Trono, Karina Gabriela (Elsevier, 2020-07)Previous studies have shown the presence of bovine leukemia virus (BLV) in colostrum and milk of naturally infected cows. The relationship between virus or provirus and specific antibodies in these secretions is particular ... -
Guía para la crianza y mantenimiento de terneros privados de calostro para su utilización como modelo animal
Malacari, Darío Amilcar (Ediciones INTA, 2016)Este manual está dirigido al personal involucrado en la utilización del modelo TPC con fines científicos. Contiene indicaciones sobre el protocolo de nutrición sanitario y de manejo de terneros privados de calostro desde ... -
Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
Bucafusco, Danilo; Pereyra, Walter Rodrigo; Mansilla, Florencia Celeste; Malacari, Darío Amilcar; Juncos, María S.; Di Giacomo, Sebastián; Ayude, Andrea Fabiana; Perez Filgueira, Daniel Mariano; Capozzo, Alejandra Victoria (Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
In vitro and in vivo characterization of a typical and a high pathogenic bovine viral diarrhea virus type ii strains
Malacari, Darío Amilcar; Pecora, Andrea; Perez Aguirreburialde, Maria Sol; Cardoso, Nancy Patricia; Odeon, Anselmo Carlos; Capozzo, Alejandra Victoria (Frontiers Media, 2018-04)Non-cytopathic (ncp) type 2 bovine viral diarrhea virus (BVDV-2) is widely prevalent in Argentina causing high mortality rates in cattle herds. In this study, we characterized an Argentinean ncp BVDV-2 field isolate (98-124) ... -
Pestivirus emergentes HoBi : impacto en salud animal y su importancia como contaminante de insumos biotecnológicos
Pecora, Andrea; Pérez Aguirreburualde, María Sol; Malacari, Darío Amilcar; Zabal, Osvaldo Alfredo; Bauermann, Fernando Viçosa; Ridpath, Julia; Dus Santos, Maria Jose (Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2016-11-02)Los virus HoBi son un grupo de Pestivirus emergentes que afecta a bovinos y bubalinos y son contaminantes muy comunes de productos biológicos. Luego de ser identificados por primera vez en Alemania a partir muestras ... -
Serologic evidence of HoBi-like virus circulation in Argentinean water buffalo
Pecora, Andrea; Perez Aguirreburualde, María Sol; Malacari, Darío Amilcar; Zabal, Osvaldo Alfredo; Sala, Juan Manuel; Konrad, Jose Luis; Caspe, Sergio Gaston; Bauermann, Fernando; Ridpath, Julia; Dus Santos, Maria Jose (2017-11)HoBi-like pestiviruses (also known as bovine viral diarrhea virus 3) have been sporadically reported from naturally infected cattle in Brazil, Asia, and Europe. Although HoBi-like viruses seem to be endemic in Brazilian ... -
Systemic Foot-and-Mouth Disease Vaccination in Cattle Promotes Specific Antibody-Secreting Cells at the Respiratory Tract and Triggers Local Anamnestic Responses upon Aerosol Infection
Pega, Juan Franco; Di Giacomo, Sebastián; Bucafusco, Danilo; Schammas, Juan Manuel; Malacari, Darío Amilcar; Barrionuevo, Florencia Mariel; Capozzo, Alejandra Victoria; Rodríguez, L.L.; Borca, Manuel Victor; Perez Filgueira, Daniel Mariano (2015-09)Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting biungulate species. Commercial vaccines, formulated with inactivated FMD virus (FMDV), are regularly used worldwide to control the disease. Here, ...