• Characterization of a Nanovaccine Platform Based on an α1,2- Mannobiose Derivative Shows Species-non-specific Targeting to Human, Bovine, Mouse, and Teleost Fish Dendritic Cells 

      Pappalardo, Juan Sebastián; Salmaso, Stefano; Levchenko, Tatyana S.; Mastrotto, Francesca; Bersani, Sara; Vermeulen, Monica; Ghersa, Federica; Quattrocchi, Valeria; Zamorano, Patricia Ines; Hartner, William C.; Toniutti, Micaela; Musacchio, Tiziana; Torchilin, Vladimir P. (ACS Publications, 2021-07)
      Dendritic cells serve as the main immune cells that trigger the immune response. We developed a simple and cost-effective nanovaccine platform based on the α1′,2-mannobiose derivative for dendritic cell targeting. In ...
    • Dendritic cell targeting in cultured fish in Argentina for vaccine development 

      Ghersa, Federica; Soria, Ivana; Quattrocchi, Valeria; Gammella, Mariela; Langellotti, Cecilia Ana; Zamorano, Patricia Ines; Rauque, Carlos Alejandro; Pappalardo, Juan Sebastián (Edición del Autor, 2019)
      In Argentina two main species present an important economic value, these are Pacú (Piaractus mesopotamicus, Pm) and Rainbow Trout (Oncorhynchus mykiss, Om). Due to stress and changing environmental conditions cultured fish ...
    • Early protection against foot-and-mouth disease virus in cattle using an inactivated vaccine formulated with Montanide ESSAI IMS D 12802 VG PR adjuvant 

      Quattrocchi, Valeria; Pappalardo, Juan Sebastián; Langellotti, Cecilia Ana; Smitsaart, Eliana N.; Fondevila, Norberto Antonio; Zamorano, Patricia Ines (Elsevier, 2014-04-17)
      Foot and mouth disease is an acute disease of cattle with a broad distribution around the world. Due to the fast spread of FMDV infections, control measures must be applied immediately after an outbreak, such as the use ...
    • Effects of polydopamine-passivation on the optical properties of carbon dots and its potential use in vivo 

      Pappalardo, Juan Sebastián; Macairan, Jun-Ray; Macina, Alexia; Poulhazan, Alexandre; Quattrocchi, Valeria; Marcotte, Isabelle; Naccache, Rafik (Royal Society of Chemistry, 2020-07)
      Passivation of carbon dots via heteroatom doping has been shown to enhance their optical properties and tune their fluorescence signature. Additionally, the incorporation of polymeric precursors in carbon dot synthesis has ...
    • Hacia una vacuna contra el Coronavirus causante de la Covid-19 

      Mignaqui, Ana Clara; Ghersa, Federica; Marcellino, Romanela; Faraldo, Joaquin; Carignano, María de los Angeles; Tatsch, Veronica; De la Puente, Eduardo; Pappalardo, Juan Sebastián (EEA Bariloche, INTA, 2021-08)
      En el Grupo de Nanomedicina Veterinaria del IFAB (INTA EEA Bariloche/CONICET), junto a la Dirección Médica de Laboratorios Bagó S.A., estamos trabajando en el desarrollo de una vacuna génica contra SARS-CoV-2, económica, ...
    • Interaction between natural magnetite sub-micrometric particles and the Fasciola hepatica egg: the role of the exposed surface area 

      Raineri, Mariana; Lima Jr., Enio; Larroza, Marcela Patricia; Moreno, Mario Sergio; Vásquez Mansilla, Marcelo; Pappalardo, Juan Sebastián; Zysler, Roberto Daniel (Elsevier, 2019)
      Fasciolosis is a zoonotic world widely distributed disease caused by the liver fluke Fasciola hepatica, which affects animals and occasionally humans. On the other hand, natural iron oxide particles like magnetite are ...
    • Isolation and molecular characterization of Clostridium perfringens from healthy Merino lambs in Patagonia region, Argentina 

      Mignaqui, Ana Clara; Marcellino, Romanela; Pappalardo, Juan Sebastián; Robles, Carlos Alejandro; Ronco, T.; Nonnemann, B.; Pedersen, K. (2016)
      The presence and molecular characterization of Clostridium perfringens in healthy Merino lambs over a six-month period was investigated in this study. Overall, a high prevalence of C. perfringens was detected, even in ...
    • MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1 

      Kornuta, Claudia Alejandra; Bidart, , Juan Esteban; Soria, Ivana; Gammella, Mariela; Quattrocchi, Valeria; Pappalardo, Juan Sebastián; Salmaso, Stefano; Torchilin, Vladimir P.; Cheuquepan Valenzuel, Felipe Andres; Hecker, Yanina; Moore, Dadin P.; Zamorano, Patricia Ines; Langellotti, Cecilia Ana (Wiley, 2021-03)
      New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ...
    • Piensos a base de insectos para alimentación animal 

      Lenz, Desiree; Pappalardo, Juan Sebastián; Pazos, Adriana Alejandra; Mutti, Federico Esteban; Gallardo, Guillermo Santiago; Aparicio, Alejandro Gabriel; Pietrantuono, Ana Laura; Rauque Perez, Carlos Alejandro; Murano, Mariana; Fernandez Arhex, Valeria Cristina (Plataforma Agraria Libre de Canarias (PALCA), 2022)
      Los insectos proporcionan proteínas, materia grasa y vitaminas de alta calidad. La formulación de piensos proteicos a base de insectos constituye una alternativa sustentable en comparación a los convencionales utilizados ...